The vacuolar ATPases (V-ATPases) are a family of proton pumps that couple ATP hydrolysis
to proton transport into intracellular compartments and across the plasma membrane. They …

Malignant infantile osteopetrosis (MIOP) is a rare hereditary disorder characterized by
excessive bone overgrowth due to a defect in bone marrow resorption by osteoclasts. In …

Discovery that mutations in TCIRG1 (also known as Atp6i) gene are responsible for most
instances of autosomal recessive osteopetrosis (ARO) heralded a new era for …

The osteopetroses and related sclerosing bone dysplasias can have a broad range of
manifestations. Especially in the milder forms, sandwich vertebrae are an easily …

A proteomic study on the tibial subchondral bone in guinea pigs with spontaneous
osteoarthritis was performed to investigate the molecular alterations that occur in early …

Background Osteopetrosis is characterized by increased bone density and bone marrow
cavity stenosis due to a decrease in the number of osteoclasts or the dysfunction of their …

Background: High bone mass (HBM) disorders are a group of clinically and genetically
heterogeneous bone diseases characterized by increased bone density on radiographs …

Antecedentes: La osteopetrosis es un grupo heterogéneo de enfermedades que se
caracterizan por aumento de la densidad ósea debido a anomalías en la diferenciación o …

Antecedentes: La osteopetrosis es un grupo heterogéneo de enfermedades que se
caracterizan por aumento de la densidad ósea debido a anomalías en la diferenciación o …