[HTML][HTML] Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Advanced strategies for overcoming endosomal/lysosomal barrier in nanodrug delivery

C Qiu, F Xia, J Zhang, Q Shi, Y Meng, C Wang, H Pang… - Research, 2023 - spj.science.org
Nanocarriers have therapeutic potential to facilitate drug delivery, including biological
agents, small-molecule drugs, and nucleic acids. However, their efficiency is limited by …

A new era in posterior segment ocular drug delivery: Translation of systemic, cell-targeted, dendrimer-based therapies

RM Kannan, I Pitha, KS Parikh - Advanced Drug Delivery Reviews, 2023 - Elsevier
Vision impairment and loss due to posterior segment ocular disorders, including age-related
macular degeneration and diabetic retinopathy, are a rapidly growing cause of disability …

[HTML][HTML] Preparation and application of calcium phosphate nanocarriers in drug delivery

C Qiu, Y Wu, Q Guo, Q Shi, J Zhang, Y Meng, F Xia… - Materials Today Bio, 2022 - Elsevier
Calcium phosphate nanoparticles represent promising materials for drug delivery because
of its favorable properties, including biocompatibility, biodegradability and strong affinity for …

[HTML][HTML] Overview of recent advances in nano-based ocular drug delivery

LC Liu, YH Chen, DW Lu - International Journal of Molecular Sciences, 2023 - mdpi.com
Ocular diseases profoundly impact patients' vision and overall quality of life globally.
However, effective ocular drug delivery presents formidable challenges within clinical …

[HTML][HTML] Optimization of an injectable hydrogel depot system for the controlled release of retinal-targeted hybrid nanoparticles

I Ottonelli, A Bighinati, E Adani, F Loll, R Caraffi… - Pharmaceutics, 2022 - mdpi.com
A drawback in the development of treatments that can reach the retina is the presence of
barriers in the eye that restrain compounds from reaching the target. Intravitreal injections …

Enhanced Ocular Delivery of Beva via Ultra‐Small Polymeric Micelles for Noninvasive Anti‐VEGF Therapy

R Yang, S Tang, X Xie, C Jin, Y Tong… - Advanced …, 2024 - Wiley Online Library
Pathological ocular neovascularization resulting from retinal ischemia constitutes a major
cause of vision loss. Current anti‐VEGF therapies rely on burdensome intravitreal injections …

[HTML][HTML] A bibliometric analysis of apoptosis in glaucoma

JH Zhang, MJ Wang, YT Tan, J Luo… - Frontiers in …, 2023 - frontiersin.org
Background Glaucoma is the first irreversible and second blindness disease, which is
characterized by the death of retinal ganglion cells (RGCs) and degeneration of the optic …

[HTML][HTML] Nanomedicine: Technologies and Applications

M Farrokhi, F Taheri, M Farrokhi, YEK Tosi… - Kindle, 2024 - preferpub.org
Nanomedicine is an innovative field that merges nanotechnology with medicine, aiming to
enhance diagnosis, treatment, and prevention of diseases at the molecular level. This …

[HTML][HTML] Liposome-Mediated Delivery Improves the Efficacy of Lisosan G against Retinopathy in Diabetic Mice

R Amato, A Melecchi, L Pucci, A Canovai, S Marracci… - Cells, 2023 - mdpi.com
Nutraceuticals are natural substances whose anti-oxidant and anti-inflammatory properties
may be used to treat retinal pathologies. Their efficacy is limited by poor bioavailability …