The role of goblet cells and mucus in intestinal homeostasis

JK Gustafsson, MEV Johansson - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestinal tract faces numerous challenges that require several layers of defence. The
tight epithelium forms a physical barrier that is further protected by a mucus layer, which …

[HTML][HTML] Current sampling methods for gut microbiota: a call for more precise devices

Q Tang, G Jin, G Wang, T Liu, X Liu… - Frontiers in cellular and …, 2020 - frontiersin.org
The development of next-generation sequencing technology has enabled researchers to
explore and understand the gut microbiome from a broader and deeper perspective …

[HTML][HTML] Dysbiosis of human gut microbiome in young-onset colorectal cancer

Y Yang, L Du, D Shi, C Kong, J Liu, G Liu, X Li… - Nature …, 2021 - nature.com
The incidence of sporadic young-onset colorectal cancer (yCRC) is increasing. A significant
knowledge gap exists in the gut microbiota and its diagnostic value for yCRC patients …

Scutellaria baicalensis Georgi polysaccharide ameliorates DSS-induced ulcerative colitis by improving intestinal barrier function and modulating gut microbiota

L Cui, X Guan, W Ding, Y Luo, W Wang, W Bu… - International Journal of …, 2021 - Elsevier
The aim of this study was to investigate the effect of a polysaccharide from Scutellaria
baicalensis Georgi on UC. Gut microbiota dysbiosis is a worldwide problem associating with …

Differences in gut microbiota in patients with vs without inflammatory bowel diseases: a systematic review

R Pittayanon, JT Lau, GI Leontiadis, F Tse, Y Yuan… - Gastroenterology, 2020 - Elsevier
Background & Aims Altering the intestinal microbiota has been proposed as a treatment for
inflammatory bowel diseases (IBDs), but there are no established associations between …

[HTML][HTML] The role of Enterobacteriaceae in gut microbiota dysbiosis in inflammatory bowel diseases

V Baldelli, F Scaldaferri, L Putignani, F Del Chierico - Microorganisms, 2021 - mdpi.com
Inflammatory bowel diseases (IBDs) are a group of chronic gastrointestinal inflammatory
diseases with unknown etiology. There is a combination of well documented factors in their …

Introduction to the human gut microbiota

E Thursby, N Juge - Biochemical journal, 2017 - portlandpress.com
The human gastrointestinal (GI) tract harbours a complex and dynamic population of
microorganisms, the gut microbiota, which exert a marked influence on the host during …

[HTML][HTML] Identification of shared and disease-specific host gene–microbiome associations across human diseases using multi-omic integration

S Priya, MB Burns, T Ward, RAT Mars… - Nature …, 2022 - nature.com
While gut microbiome and host gene regulation independently contribute to gastrointestinal
disorders, it is unclear how the two may interact to influence host pathophysiology. Here we …

Intestinal Microbiota in Cardiovascular Health and Disease: JACC State-of-the-Art Review

WHW Tang, F Bäckhed, U Landmesser… - Journal of the American …, 2019 - jacc.org
Despite major strides in reducing cardiovascular disease (CVD) burden with modification of
classic CVD risk factors, significant residual risks remain. Recent discoveries that linked …

Proteobacteria: microbial signature of dysbiosis in gut microbiota

NR Shin, TW Whon, JW Bae - Trends in biotechnology, 2015 - cell.com
Recent advances in sequencing techniques, applied to the study of microbial communities,
have provided compelling evidence that the mammalian intestinal tract harbors a complex …