Considering how biological sex impacts immune responses and COVID-19 outcomes
A male bias in mortality has emerged in the COVID-19 pandemic, which is consistent with
the pathogenesis of other viral infections. Biological sex differences may manifest …
the pathogenesis of other viral infections. Biological sex differences may manifest …
Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities
LA Bienvenu, J Noonan, X Wang… - Cardiovascular …, 2020 - academic.oup.com
The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …
Androgen conspires with the CD8+ T cell exhaustion program and contributes to sex bias in cancer
Sex bias exists in the development and progression of nonreproductive organ cancers, but
the underlying mechanisms are enigmatic. Studies so far have focused largely on sexual …
the underlying mechanisms are enigmatic. Studies so far have focused largely on sexual …
Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity
C Yang, J Jin, Y Yang, H Sun, L Wu, M Shen, X Hong… - Immunity, 2022 - cell.com
The incidence and mortality rates of many non-reproductive human cancers are generally
higher in males than in females. However, the immunological mechanism underlying sexual …
higher in males than in females. However, the immunological mechanism underlying sexual …
Sex hormone signaling and regulation of immune function
Immune responses to antigens, including innocuous, self, tumor, microbial, and vaccine
antigens, differ between males and females. The quest to uncover the mechanisms for …
antigens, differ between males and females. The quest to uncover the mechanisms for …
Immunizing lithium metal anodes against dendrite growth using protein molecules to achieve high energy batteries
The practical applications of lithium metal anodes in high-energy-density lithium metal
batteries have been hindered by their formation and growth of lithium dendrites. Herein, we …
batteries have been hindered by their formation and growth of lithium dendrites. Herein, we …
[HTML][HTML] B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells
The long non-coding RNA (lncRNA) XIST establishes X chromosome inactivation (XCI) in
female cells in early development and thereafter is thought to be largely dispensable. Here …
female cells in early development and thereafter is thought to be largely dispensable. Here …
Worse progression of COVID‐19 in men: is testosterone a key factor?
VA Giagulli, E Guastamacchia, T Magrone, E Jirillo… - …, 2021 - Wiley Online Library
Background The novel severe acute respiratory syndrome coronavirus (SARS‐CoV‐2)
disease 2019 (COVID‐19) seems to have a worse clinical course among infected men …
disease 2019 (COVID‐19) seems to have a worse clinical course among infected men …
Immune clearance of senescent cells to combat ageing and chronic diseases
Senescent cells are generally characterized by permanent cell cycle arrest, metabolic
alteration and activation, and apoptotic resistance in multiple organs due to various …
alteration and activation, and apoptotic resistance in multiple organs due to various …
Chemokines in chronic pain: cellular and molecular mechanisms and therapeutic potential
Chronic pain resulting from nerve injury, tissue inflammation, and tumor invasion or
treatment, is a major health problem impacting the quality of life and producing a significant …
treatment, is a major health problem impacting the quality of life and producing a significant …