The structure and post-translational processing of the SARS-CoV-2 spike glycoprotein (S) is
intimately associated with the function of the virus and of sterilising vaccines. The surface of …

A key aspect of successful viral vaccine design is the elicitation of neutralizing antibodies
targeting viral attachment and fusion glycoproteins that embellish viral particles. This …

The SARS-CoV-2 Omicron (B. 1.1. 529) variant possesses numerous spike (S) mutations
particularly in the S receptor-binding domain (S-RBD) that significantly improve …

Characterization of protein glycosylation by tandem mass spectrometry remains challenging
owing to the vast diversity of oligosaccharides bound to proteins, the variation in …

Glycosylation is one of the post-translational modifications with more than 50% of human
proteins being glycosylated. The exact nature and chemical composition of glycans are …

N-and O-glycans are both important constituents of viral envelope glycoproteins. O-linked
glycosylation can be initiated by any of 20 different human polypeptide O …

The receptor binding domain (RBD) of the SARS‐CoV‐2 spike (S)‐protein is a prime target
of virus‐neutralizing antibodies present in convalescent sera of COVID‐19 patients and thus …

The interaction between the receptor‐binding domain (RBD) of the spike glycoprotein of
SARS‐CoV‐2 and the peptidase domain of the human angiotensin‐converting enzyme 2 …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the cause of the on‐
going global pandemic of coronavirus disease 2019 (COVID‐19) that continues to pose a …

The world-wide COVID-19 pandemic has promoted a series of alternative vaccination
strategies aiming to elicit neutralizing adaptive immunity in the human host. However …