Strategies to combat antimicrobial resistance: anti-plasmid and plasmid curing

MMC Buckner, ML Ciusa… - FEMS microbiology …, 2018 - academic.oup.com
Antimicrobial resistance (AMR) is a global problem hindering treatment of bacterial
infections, rendering many aspects of modern medicine less effective. AMR genes (ARGs) …

Physiological aspects: Part 1 in a series of papers devoted to surfactants in microbiology and biotechnology

JD Van Hamme, A Singh, OP Ward - Biotechnology advances, 2006 - Elsevier
Surfactants, both chemical and biological, are amphiphilic compounds which can reduce
surface and interfacial tensions by accumulating at the interface of immiscible fluids and …

Coupling the CRISPR/Cas9 system with lambda red recombineering enables simplified chromosomal gene replacement in Escherichia coli

ME Pyne, M Moo-Young, DA Chung… - Applied and …, 2015 - Am Soc Microbiol
To date, most genetic engineering approaches coupling the type II Streptococcus pyogenes
clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system to lambda …

Targeting plasmids to limit acquisition and transmission of antimicrobial resistance

CO Vrancianu, LI Popa, C Bleotu… - Frontiers in …, 2020 - frontiersin.org
Antimicrobial resistance (AMR) is a significant global threat to both public health and the
environment. The emergence and expansion of AMR is sustained by the enormous diversity …

Developing a CRISPR‐assisted base‐editing system for genome engineering of Pseudomonas chlororaphis

SJ Yue, P Huang, S Li, YY Cai, W Wang… - Microbial …, 2022 - Wiley Online Library
Pseudomonas chlororaphis is a non‐pathogenic, plant growth‐promoting rhizobacterium
that secretes phenazine compounds with broad‐spectrum antibiotic activity. Currently …

Transcriptional Responses of Enterococcus faecalis V583 to Bovine Bile and Sodium Dodecyl Sulfate

M Solheim, A Aakra, H Vebø, L Snipen… - Applied and …, 2007 - Am Soc Microbiol
Resistance to bile is a prerequisite property of the gastrointestinal bacterial flora. Bile acids
are powerful detergents, and resistance to sodium dodecyl sulfate (SDS) has therefore often …

Curing of Plasmid pXO1 from Bacillus anthracis Using Plasmid Incompatibility

X Liu, D Wang, H Wang, E Feng, L Zhu, H Wang - PloS one, 2012 - journals.plos.org
The large plasmid pXO1 encoding the anthrax toxin is important for the virulence of Bacillus
anthracis. It is essential to cure pXO1 from B. anthracis to evaluate its role in the …

Inhibition effect of flavophospholipol on conjugative transfer of the extended-spectrum β-lactamase and vanA genes

H Kudo, M Usui, W Nagafuji, K Oka… - The Journal of …, 2019 - nature.com
Flavophospholipol (FPL) is an antimicrobial feed additive that has been approved for use in
livestock animals and has the potential to decrease horizontal dissemination of antimicrobial …

Curing of four different plasmids in Yersinia pestis using plasmid incompatibility

B Ni, Z Du, Z Guo, Y Zhang… - Letters in applied …, 2008 - academic.oup.com
Aims: Plasmids are critical for the pathogenicity of Yersinia pestis. In order to carry out a
systematic investigation of their role in pathogenesis, we cured plasmids from Y. pestis …

Enhancement of UV Light Sensitivity of a Vibrio parahaemolyticus O3:K6 Pandemic Strain Due to Natural Lysogenization by a Telomeric Phage

B Zabala, K García, RT Espejo - Applied and environmental …, 2009 - Am Soc Microbiol
ABSTRACT The Vibrio parahaemolyticus O3: K6 pandemic clonal strain was first observed
in southern Chile in 2004 and has since caused approximately 8,000 seafood-related …