[HTML][HTML] Zebrafish models of human motor neuron diseases: advantages and limitations

PJ Babin, C Goizet, D Raldúa - Progress in neurobiology, 2014 - Elsevier
Motor neuron diseases (MNDs) are an etiologically heterogeneous group of disorders of
neurodegenerative origin, which result in degeneration of lower (LMNs) and/or upper motor …

Zebrafish models of cardiovascular disease

D Bournele, D Beis - Heart failure reviews, 2016 - Springer
Cardiovascular disease (CVD) is one of the leading causes of death worldwide. The most
significant risk factors associated with the development of heart diseases include genetic …

[HTML][HTML] Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche

OJ Tamplin, EM Durand, LA Carr, SJ Childs… - Cell, 2015 - cell.com
Hematopoietic stem and progenitor cells (HSPCs) can reconstitute and sustain the entire
blood system. We generated a highly specific transgenic reporter of HSPCs in zebrafish …

Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward …

A Alzualde, M Behl, NS Sipes, JH Hsieh, A Alday… - Neurotoxicology and …, 2018 - Elsevier
Following the voluntary phase-out of brominated flame retardants (BFRs) due to their
environmental persistence and toxicity, the organophosphorus flame retardants (OPFRs) are …

ZebraBeat: a flexible platform for the analysis of the cardiac rate in zebrafish embryos

E De Luca, GM Zaccaria, M Hadhoud, G Rizzo… - Scientific Reports, 2014 - nature.com
Heartbeat measurement is important in assesssing cardiac function because variations in
heart rhythm can be the cause as well as an effect of hidden pathological heart conditions …

In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration

WY Choi, M Gemberling, J Wang, JE Holdway… - …, 2013 - journals.biologists.com
Adult mammalian cardiomyocytes have little capacity to proliferate in response to injury, a
deficiency that underlies the poor regenerative ability of human hearts after myocardial …

The developing zebrafish (Danio rerio): A vertebrate model for high‐throughput screening of chemical libraries

CA Lessman - Birth Defects Research Part C: Embryo Today …, 2011 - Wiley Online Library
The zebrafish, Danio rerio, a small, tropical freshwater species native to Pakistan and India,
has become a National Institutes of Health‐sanctioned model organism and, due to its many …

Animal models of tuberculosis: Lesson learnt

AK Singh, UD Gupta - Indian Journal of Medical Research, 2018 - journals.lww.com
Tuberculosis (TB) remains a leading cause of death globally among infectious diseases that
has killed more numbers of people than any other infectious diseases. Animal models have …

The Zebrafish: A Powerful Platform for In Vivo, HTS Drug Discovery

C Delvecchio, J Tiefenbach… - Assay and drug …, 2011 - liebertpub.com
The zebrafish (Danio rerio) is an emerging vertebrate model for drug discovery that permits
whole animal drug screens with excellent throughput, combined with ease of use and low …

A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents

SH Oehlers, MV Flores, KS Okuda… - Developmental …, 2011 - Wiley Online Library
Inflammatory bowel disease (IBD) results from dysfunctional interactions between the
intestinal immune system and microbiota, influenced by host genetic susceptibility. Because …