Editorial Perspective: Bridging the translational neuroscience gap in autism–development of the 'shiftability'paradigm

TP Whelan, E Daly, NA Puts… - Journal of Child …, 2024 - Wiley Online Library
Clinical trials of pharmacological candidates targeting the core features of autism have
largely failed. This is despite evidence linking differences in multiple neurochemical systems …

[HTML][HTML] The effects of pramipexole on motivational vigour during a saccade task: a placebo-controlled study in healthy adults

SK Au-Yeung, DC Halahakoon, A Kaltenboeck… - …, 2024 - Springer
Motivation allows us to energise actions when we expect reward and is reduced in
depression. This effect, termed motivational vigour, has been proposed to rely on central …

D2/D3 receptor agonism: paving the way for a new therapeutic target for taste disorders in Parkinson's disease and other conditions?

E Mantovani, S Tamburin - International Journal of …, 2022 - academic.oup.com
Chemosensory (ie, olfaction and taste) dysfunction is common in neurodegenerative (eg,
Parkinson's disease, Alzheimer's disease, and dementia), psychiatric (eg, depression …

Interaction of dihydrofuran-2-one and its derivatives with either MAO-B or COMT enzymes using a theoretical model

L Figueroa-Valverde… - Brazilian Journal …, 2024 - periodicos.cerradopub.com.br
There are several drugs for treating Parkinson's such as L-Dopa, carbidopa, benserazide,
entacapone, bromocriptine, safinamide, rasagiline, and others. However, some of these …