HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management
Abstract Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …
HPV post-infection microenvironment and cervical cancer
Y Yuan, X Cai, F Shen, F Ma - Cancer Letters, 2021 - Elsevier
Human papillomavirus (HPV) is the most common sexually transmitted virus worldwide.
More than 99% of cervical cancer cases are associated with certain types of HPVs, termed …
More than 99% of cervical cancer cases are associated with certain types of HPVs, termed …
The effect of hypoxia on the expression of CXC chemokines and CXC chemokine receptors—a review of literature
J Korbecki, K Kojder, P Kapczuk, P Kupnicka… - International journal of …, 2021 - mdpi.com
Hypoxia is an integral component of the tumor microenvironment. Either as chronic or
cycling hypoxia, it exerts a similar effect on cancer processes by activating hypoxia-inducible …
cycling hypoxia, it exerts a similar effect on cancer processes by activating hypoxia-inducible …
The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation
JA Scarth, MR Patterson… - Journal of General …, 2021 - microbiologyresearch.org
Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …
Oncolytic viruses as engineering platforms for combination immunotherapy
K Twumasi-Boateng, JL Pettigrew, YYE Kwok… - Nature Reviews …, 2018 - nature.com
To effectively build on the recent successes of immune checkpoint blockade, adoptive T cell
therapy and cancer vaccines, it is critical to rationally design combination strategies that will …
therapy and cancer vaccines, it is critical to rationally design combination strategies that will …
Papillomavirus immune evasion strategies target the infected cell and the local immune system
Persistent infection with human papillomavirus (HPV) initiates~ 5% of all human cancers,
and particularly cervical and oropharyngeal cancers. HPV vaccines prevent HPV infection …
and particularly cervical and oropharyngeal cancers. HPV vaccines prevent HPV infection …
Host-directed antiviral therapy
Antiviral drugs have traditionally been developed by directly targeting essential viral
components. However, this strategy often fails due to the rapid generation of drug-resistant …
components. However, this strategy often fails due to the rapid generation of drug-resistant …
Epigenetics and allergy: from basic mechanisms to clinical applications
DP Potaczek, H Harb, S Michel, BA Alhamwe… - …, 2017 - Taylor & Francis
Allergic diseases are on the rise in the Western world and well-known allergy-protecting and-
driving factors such as microbial and dietary exposure, pollution and smoking mediate their …
driving factors such as microbial and dietary exposure, pollution and smoking mediate their …
High-risk human papillomaviral oncogenes E6 and E7 target key cellular pathways to achieve oncogenesis
Infection with high-risk human papillomavirus (HPV) has been linked to several human
cancers, the most prominent of which is cervical cancer. The integration of the viral genome …
cancers, the most prominent of which is cervical cancer. The integration of the viral genome …
[HTML][HTML] Evasion of host immune defenses by human papillomavirus
A majority of human papillomavirus (HPV) infections are asymptomatic and self-resolving in
the absence of medical interventions. Various innate and adaptive immune responses, as …
the absence of medical interventions. Various innate and adaptive immune responses, as …