Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapy

DP Dittmer, B Damania - The Journal of clinical …, 2016 - Am Soc Clin Investig
Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is
the etiologic agent underlying Kaposi sarcoma, primary effusion lymphoma, and multicentric …

[HTML][HTML] Complement and viral pathogenesis

KA Stoermer, TE Morrison - Virology, 2011 - Elsevier
The complement system functions as an immune surveillance system that rapidly responds
to infection. Activation of the complement system by specific recognition pathways triggers a …

KSHV 2.0: a comprehensive annotation of the Kaposi's sarcoma-associated herpesvirus genome using next-generation sequencing reveals novel genomic and …

C Arias, B Weisburd, N Stern-Ginossar… - PLoS …, 2014 - journals.plos.org
Productive herpesvirus infection requires a profound, time-controlled remodeling of the viral
transcriptome and proteome. To gain insights into the genomic architecture and gene …

KSHV (HHV8) vaccine: promises and potential pitfalls for a new anti-cancer vaccine

C Casper, L Corey, JI Cohen, B Damania, AA Gershon… - npj Vaccines, 2022 - nature.com
Seven viruses cause at least 15% of the total cancer burden. Viral cancers have been
described as the “low-hanging fruit” that can be potentially prevented or treated by new …

[HTML][HTML] Complement evasion strategies of viruses: an overview

P Agrawal, R Nawadkar, H Ojha, J Kumar… - Frontiers in …, 2017 - frontiersin.org
Being a major first line of immune defense, the complement system keeps a constant vigil
against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and …

Molecular biology of KSHV lytic reactivation

P Purushothaman, T Uppal, SC Verma - Viruses, 2015 - mdpi.com
Kaposi's sarcoma-associated herpesvirus (KSHV) primarily persists as a latent episome in
infected cells. During latent infection, only a limited number of viral genes are expressed that …

Towards better understanding of KSHV life cycle: from transcription and posttranscriptional regulations to pathogenesis

L Yan, V Majerciak, ZM Zheng, K Lan - Virologica Sinica, 2019 - Springer
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …

Kaposi's sarcoma–associated herpesvirus immunoevasion and tumorigenesis: two sides of the same coin?

PS Moore, Y Chang - Annual Reviews in Microbiology, 2003 - annualreviews.org
▪ Abstract Kaposi's sarcoma–associated herpesvirus (KSHV)[or human herpesvirus 8 (HHV-
8)] is the most frequent cause of malignancy among AIDS patients. KSHV and related …

Humoral innate immune response and disease

SN Shishido, S Varahan, K Yuan, X Li, SD Fleming - Clinical immunology, 2012 - Elsevier
The humoral innate immune response consists of multiple components, including the
naturally occurring antibodies (NAb), pentraxins and the complement and contact cascades …

Kaposi's sarcoma-associated herpesvirus immune modulation: an overview

SAR Rezaee, C Cunningham… - Journal of General …, 2006 - microbiologyresearch.org
Kaposi's sarcoma-associated herpesvirus (KSHV) is the most recently discovered human
herpesvirus. It is the aetiological agent of Kaposi's sarcoma (KS), a tumour frequently …