Continuous drug product manufacturing is slowly being implemented in the pharmaceutical
industry. Although the benefits related to the quality and cost of continuous manufacturing …

While continuous manufacturing (CM) of pharmaceutical solid-based drug products has
been shown to be advantageous for improving the product quality and process efficiency in …

Residence time distributions (RTDs) are quickly becoming an important component of the
quality control strategy for continuous manufacturing (CM) of pharmaceutical products …

Continuous twin screw wet granulation is one of the key continuous manufacturing
technologies that have gained significant interest in the pharmaceutical industry as well as …

Despite significant advances in the research domain of continuous twin screw granulation,
limited information is currently available on the impact of raw material properties, especially …

This work presents a granule size prediction approach applicable to diverse formulations
containing new active pharmaceutical ingredients (APIs) in continuous twin-screw wet …

Residence time distribution (RTD) has been widely applied across various fields of chemical
engineering, including pharmaceutical manufacturing, for applications such as material …

In this study, a quantitative relationship between material properties, process settings and
screw feeding responses of a high-throughput feeder was established via multivariate …

Extended release formulations play a crucial role in the pharmaceutical industry by
maintaining steady plasma levels, reducing side effects, and improving therapeutic …

In this study, quantitative relationships were established between blend properties, process
settings and blending responses via multivariate data-analysis. Four divergent binary blends …