A comprehensive compilation of SUMO proteomics
IA Hendriks, ACO Vertegaal - Nature reviews Molecular cell biology, 2016 - nature.com
Small ubiquitin-like modifiers (SUMOs) are essential for the regulation of several cellular
processes and are potential therapeutic targets owing to their involvement in diseases such …
processes and are potential therapeutic targets owing to their involvement in diseases such …
Sumoylation on its 25th anniversary: mechanisms, pathology, and emerging concepts
Sumoylation is an essential post‐translational modification intimately involved in a diverse
range of eukaryotic cellular mechanisms. Small ubiquitin‐like modifier (SUMO) protein …
range of eukaryotic cellular mechanisms. Small ubiquitin‐like modifier (SUMO) protein …
Histone sumoylation and chromatin dynamics
HY Ryu, M Hochstrasser - Nucleic Acids Research, 2021 - academic.oup.com
Chromatin structure and gene expression are dynamically controlled by post-translational
modifications (PTMs) on histone proteins, including ubiquitylation, methylation, acetylation …
modifications (PTMs) on histone proteins, including ubiquitylation, methylation, acetylation …
A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation
Topoisomerases form transient covalent DNA cleavage complexes to perform their
reactions. Topoisomerase I cleavage complexes (TOP1ccs) are trapped by camptothecin …
reactions. Topoisomerase I cleavage complexes (TOP1ccs) are trapped by camptothecin …
The emerging complexity of protein ubiquitination
D Komander - Biochemical society transactions, 2009 - portlandpress.com
Protein ubiquitination and protein phosphorylation are two fundamental regulatory post-
translational modifications controlling intracellular signalling events. However, the ubiquitin …
translational modifications controlling intracellular signalling events. However, the ubiquitin …
Mechanisms, regulation and consequences of protein SUMOylation
KA Wilkinson, JM Henley - Biochemical Journal, 2010 - portlandpress.com
The post-translational modification SUMOylation is a major regulator of protein function that
plays an important role in a wide range of cellular processes. SUMOylation involves the …
plays an important role in a wide range of cellular processes. SUMOylation involves the …
Atypical ubiquitin chains: new molecular signals
Ubiquitin (Ub) is a small protein modifier that regulates many biological processes, including
gene transcription, cell‐cycle progression, DNA repair, apoptosis, virus budding and …
gene transcription, cell‐cycle progression, DNA repair, apoptosis, virus budding and …
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
MH Tatham, MC Geoffroy, L Shen, A Plechanovova… - Nature cell …, 2008 - nature.com
In acute promyelocytic leukaemia (APL), the promyelocytic leukaemia (PML) protein is fused
to the retinoic acid receptor α (RAR). This disease can be treated effectively with arsenic …
to the retinoic acid receptor α (RAR). This disease can be treated effectively with arsenic …
Decoding signalling networks by mass spectrometry-based proteomics
C Choudhary, M Mann - Nature reviews Molecular cell biology, 2010 - nature.com
Signalling networks regulate essentially all of the biology of cells and organisms in normal
and disease states. Signalling is often studied using antibody-based techniques such as …
and disease states. Signalling is often studied using antibody-based techniques such as …