Effects of experimental sleep deprivation on anxiety-like behavior in animal research: Systematic review and meta-analysis

GN Pires, AG Bezerra, S Tufik, ML Andersen - … & Biobehavioral Reviews, 2016 - Elsevier
Increased acute anxiety is a commonly reported behavioral consequence of sleep
deprivation in humans. However, rodent studies conducted so far produced inconsistent …

[HTML][HTML] The effect of REM-sleep disruption on affective processing: A systematic review of human and animal experimental studies

AK Pesonen, MK Koskinen, N Vuorenhela… - Neuroscience & …, 2024 - Elsevier
Evidence on the importance of rapid-eye-movement sleep (REMS) in processing emotions
is accumulating. The focus of this systematic review is the outcomes of experimental REMS …

[HTML][HTML] TNF signaling pathway-mediated microglial activation in the PFC underlies acute paradoxical sleep deprivation-induced anxiety-like behaviors in mice

H Liu, X Huang, Y Li, K Xi, Y Han, H Mao, K Ren… - Brain, behavior, and …, 2022 - Elsevier
Acute sleep deprivation is a common condition in modern life and increases anxiety
symptoms in healthy individuals. The neuroinflammatory response induced by microglial …

Obesity and intermittent hypoxia increase tumor growth in a mouse model of sleep apnea

I Almendros, JM Montserrat, M Torres, MR Bonsignore… - Sleep medicine, 2012 - Elsevier
BACKGROUND: Intermittent hypoxia and obesity which are two pathological conditions
commonly found in patients with obstructive sleep apnea (OSA), potentially enhance cancer …

Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice

F Tai, C Wang, X Deng, R Li, Z Guo, H Quan, S Li - Brain Research Bulletin, 2020 - Elsevier
Various sleep disorders have deleterious effects on mental and cognitive performance.
Exercise, as an alternative therapeutic strategy, exerts beneficial impacts on human health …

[HTML][HTML] Sleep loss and cytokines levels in an experimental model of psoriasis

C Hirotsu, M Rydlewski, MS Araujo, S Tufik… - PloS one, 2012 - journals.plos.org
Up to 80% of people develop a cutaneous condition closely connected to their exposure to
stressful life events. Psoriasis is a chronic recurrent inflammatory skin disorder with …

Prostaglandins mediate depressive-like behaviour induced by endotoxin in mice

VN de Paiva, SNP Lima, MM Fernandes… - Behavioural brain …, 2010 - Elsevier
Sickness behaviour appears to be the expression of a central motivational state that
reorganises the organism's priorities to cope with infectious pathogens. To evaluate the …

Sleep deprivation aggravates lipopolysaccharide-induced anxiety, depression and cognitive impairment: The role of pro-inflammatory cytokines and synaptic plasticity …

YM Zhang, RM Wei, YZ Feng, KX Zhang, YJ Ge… - Journal of …, 2024 - Elsevier
Growing evidence indicates that neuroinflammation plays a critical role in anxiety,
depression, and cognitive impairment. Sleep loss disrupts the host's immune balance and …

Sleep deprivation predisposes allergic mice to neutrophilic lung inflammation

JOF Nunes, J de Souza Apostolico… - Journal of Allergy and …, 2018 - Elsevier
Background Although different studies associated sleep deprivation (SD) with systemic
inflammatory changes, the effect of sleep duration on the pathology of allergic chronic …

Paradoxical (REM) sleep deprivation in mice using the small‐platforms‐over‐water method: polysomnographic analyses and melanin‐concentrating hormone and …

S Arthaud, C Varin, N Gay, PA Libourel… - Journal of sleep …, 2015 - Wiley Online Library
Studying paradoxical sleep homeostasis requires the specific and efficient deprivation of
paradoxical sleep and the evaluation of the subsequent recovery period. With this aim, the …