DNA‐encoded library (DEL) technologies are transforming the drug discovery process,
enabling the identification of ligands at unprecedented speed and scale. DEL makes use of …

Visible Light Photoredox Catalysis Using Ruthenium Complexes in Chemical Biology - Angerani -
2019 - Chemistry – A European Journal - Wiley Online Library Skip to Article Content Skip to Article …

DNA-encoded library technologies enable the screening of synthetic molecules but have
thus far not tapped into the power of Darwinian selection with iterative cycles of selection …

Specialized cellular networks of oxidoreductases coordinate the dithiol/disulfide-exchange
reactions that control metabolism, protein regulation, and redox homeostasis. For probes to …

Peptide–oligonucleotide conjugates (POCs) are covalent constructs that link a molecule like
DNA to a synthetic peptide sequences. These materials merge the programmable self …

Peptide nucleic acid or PNA is a synthetic DNA mimic that contains a sequence of
nucleobases attached to a peptide-like backbone derived from N-2-aminoethylglycine. The …

The HCR represents a powerful tool for amplification in DNA-based circuitry and sensing
applications, yet requires the use of long DNA sequences to grant hairpin metastability. Here …

Proteins are unlikely to have emerged as the large, complex globular forms we know today.
First, the primordial protein synthesis machinery would inevitably have been inefficient, and …

We report DNA-scaffolded synergistic catalysis, a concept that combines the diverse
reaction scope of synergistic catalysis with the ability of DNA to precisely preorganize abiotic …

Quantifying the activity of key cellular redox players is crucial for understanding
physiological homeostasis and for targeting their perturbed states in pathologies, including …