Applying precision oncology principles in radiation oncology

SC Kamran, KW Mouw - JCO Precision Oncology, 2018 - ascopubs.org
Radiation therapy is a critical component in the curative management of many solid tumor
types, and advances in radiation delivery techniques during the past decade have led to …

Mutant LKB1 confers enhanced radiosensitization in combination with trametinib in KRAS-mutant non–small cell lung cancer

Y Wang, N Li, W Jiang, W Deng, R Ye, C Xu… - Clinical Cancer …, 2018 - AACR
Purpose: The MEK inhibitor trametinib radiosensitizes KRAS-mutant non–small cell lung
cancer (NSCLC) and is being tested clinically with chemoradiation. However, variability in …

[HTML][HTML] Narrative review of the emerging role of molecular biomarkers in guiding the definitive management of unresectable non-small cell lung cancer

EK Singhi, CM Gay - Translational Lung Cancer Research, 2020 - ncbi.nlm.nih.gov
The addition of PD-L1 targeting consolidation therapy to previously standard of care
concurrent chemoradiation for locally advanced, unresectable non-small cell lung cancer …

Enhancing Radiation Sensitivity In Non-Small Cell Lung Cancer

Y Wang - 2018 - digitalcommons.library.tmc.edu
Lung cancer is the leading cause of cancer-related death. While radiation therapy is one of
the standard treatments for lung cancer, the disease outcome after radiotherapy is still far …