The C. elegans insulin/IGF-1 signaling (IIS) pathway connects nutrient levels to metabolism,
growth, development, longevity, and behavior. This fundamental pathway is regulated by …

Wnt proteins are now recognized as one of the major families of developmentally important
signaling molecules, with mutations in Wnt genes displaying remarkable phenotypes in the …

In many contexts, self-renewal and differentiation of stem cells are influenced by signals
from their environment, constituting a niche. It is postulated that stem cells compete for local …

Cell-cell communication via Wnt signals represents a fundamental means by which animal
development and homeostasis are controlled. The identification of components of the Wnt …

Female chimpanzees often forage alone and do not display obvious linear dominance
hierarchies; consequently, it has been suggested that dominance is not of great importance …

Wnt proteins are lipid-modified glycoproteins that play a central role in development, adult
tissue homeostasis and disease. Secretion of Wnt proteins is mediated by the Wnt-binding …

Frizzled genes encode integral membrane proteins that function in multiple signal
transduction pathways. They have been identified in diverse animals, from sponges to …

Over the past few years, a number of studies have described the generation of transgenic
lines of zebrafish in which expression of reporters was driven by a variety of promoters …

This exploration of American women's post-World War II higher education begins with three
stories. These narratives reflect issues women faced when, as educators, they tried to plan …

The Wnt family of secreted proteins plays a crucial role in nervous system wiring. Wnts
regulate neuronal positioning, polarization, axon and dendrite development, and …