Antimicrobial peptides as an alternative for the eradication of bacterial biofilms of multi-drug resistant bacteria

JTC Pontes, AB Toledo Borges, CA Roque-Borda… - Pharmaceutics, 2022 - mdpi.com
Bacterial resistance is an emergency public health problem worldwide, compounded by the
ability of bacteria to form biofilms, mainly in seriously ill hospitalized patients. The World …

Pharmaceutical nanotechnology: Antimicrobial peptides as potential new drugs against WHO list of critical, high, and medium priority bacteria

CA Roque-Borda, PB Da Silva, MC Rodrigues… - European Journal of …, 2022 - Elsevier
Nanobiotechnology is a relatively unexplored area that has, nevertheless, shown relevant
results in the fight against some diseases. Antimicrobial peptides (AMPs) are …

Chitosan and HPMCAS double-coating as protective systems for alginate microparticles loaded with Ctx (Ile21)-Ha antimicrobial peptide to prevent intestinal …

CA Roque-Borda, MMS Saraiva, WDM Junior… - Biomaterials, 2023 - Elsevier
The incorrect use of conventional drugs for both prevention and control of intestinal
infections has contributed to a significant spread of bacterial resistance. In this way, studies …

Activity of Bacteriophage D29 Loaded on Nanoliposomes against Macrophages Infected with Mycobacterium tuberculosis

APB Silva, CA Roque-Borda, CS Carnero Canales… - Diseases, 2023 - mdpi.com
The search for new antimicrobial agents is a continuous struggle, mainly because more and
more cases of resistant strains are being reported. Mycobacterium tuberculosis (MTB) is the …

[HTML][HTML] Green synthesis of carboxy methyl chitosan based curcumin nanoparticles and its biological activity: Influence of size and conductivity

J Kabiriyel, R Jeyanthi, K Jayakumar, A Amalraj… - Carbohydrate Polymer …, 2023 - Elsevier
The exceptional and appealing qualities of the polysaccharide biopolymer chitosan, such as
biodegradability, biocompatibility and nontoxicity have been successfully utilized in the …

Antimicrobial peptides as drugs with double response against Mycobacterium tuberculosis coinfections in lung cancer

G Polinário, LMDG Primo, MABC Rosa… - Frontiers in …, 2023 - frontiersin.org
Tuberculosis and lung cancer are, in many cases, correlated diseases that can be confused
because they have similar symptoms. Many meta-analyses have proven that there is a …

Delivery Strategies of Probiotics from Nano-and Microparticles: Trends in the Treatment of Inflammatory Bowel Disease—An Overview

SA Lopes, CA Roque-Borda, JL Duarte, LD Di Filippo… - Pharmaceutics, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder, most known as
ulcerative colitis (UC) and Crohn's disease (CD), that affects the gastrointestinal tract (GIT) …

Beta‐lactam resistance and the effectiveness of antimicrobial peptides against KPC‐producing bacteria

G da Costa de Souza… - Drug Development …, 2022 - Wiley Online Library
Bacterial resistance is a problem that is giving serious cause for concern because bacterial
strains such as Acinetobacter baumannii and Pseudomonas aeruginosa are difficult to treat …

Efficacy of different encapsulation techniques on the viability and stability of diverse phage under simulated gastric conditions

SB Dlamini, AM Gigante, SPT Hooton, RJ Atterbury - Microorganisms, 2023 - mdpi.com
Salmonella causes a range of diseases in humans and livestock of considerable public
health and economic importance. Widespread antimicrobial use, particularly in intensively …

Nanobiotechnology with therapeutically relevant macromolecules from animal venoms: Venoms, toxins, and antimicrobial peptides

CA Roque-Borda, MWL Gualque, FH da Fonseca… - Pharmaceutics, 2022 - mdpi.com
Some diseases of uncontrolled proliferation such as cancer, as well as infectious diseases,
are the main cause of death in the world, and their causative agents have rapidly developed …