Polyunsaturated fatty acids (PUFAs) play multiple physiological roles. They regulate the
structure and function of cell membranes and cell growth and proliferation, and apoptosis. In …

Maternal nutrition is critically important for fetal development. Recent human studies
demonstrate a strong connection between diet during pregnancy and offspring risk for …

In this study, we hypothesized that n-3 polyunsaturated fatty acid (PUFA) deficiency during
pregnancy and lactation will make a lasting impact on brain neurogenesis and apoptosis of …

The triplication of chromosome 21 causes Down syndrome (DS), a genetic disorder that is
characterized by intellectual disability (ID). The causes of ID start in utero, leading to …

During neural development, embryonic neural stem cells (eNSCs) differentiate toward glial,
oligodendrocytic, and neuronal cells. Dysregulation of polyunsaturated fatty acids (PUFAs) …

Gestational infection causes various neurological deficits in offspring, such as age-related
spatial learning and memory (SLM) decline. How inflammation causes age-related SLM …

Abstract Purpose of Review In this review, the recent knowledge regarding the epigenetic
effects of the four most important dietary fatty acids will be discussed. Recent Findings …

Maternal obesity is a prevalent issue in the US with approximately ½ of the pregnant
population being overweight or obese at time of conception. Offspring from obese …

PUFAs serve many important biological and physiological functions within the body and are
key for the structure and function of the brain. Omega-6 and omega-3 PUFAs are found in …

Lipids in nervous system are of particular interest because of the high concentration of lipids
in brain, second only to adipose tissue, of which a major part is found in myelin. These lipids …