Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

Chronotherapeutics aim at treating illnesses according to the endogenous biologic rhythms,
which moderate xenobiotic metabolism and cellular drug response. The molecular clocks …

The role of melatonin has been extensively investigated in pathophysiological conditions,
including autism spectrum disorder (ASD). Reduced melatonin secretion has been reported …

Melatonin (MLT) exerts its physiological effects principally through two high‐affinity
membrane receptors MT1 and MT2. Understanding the exact mechanism of MLT action …

Introduction: The neurohormone melatonin is secreted by the pineal gland and shows a
circadian rhythm. It has been used in pathological conditions to evaluate its protective …

The eye is continuously exposed to solar UV radiation and pollutants, making it prone to
oxidative attacks. In fact, oxidative damage is a major cause of age‐related ocular diseases …

Melatonin is a neurohormone mainly produced by the pineal gland following a circadian
rhythm. It is characterized as a pleiotropic factor because it not only regulates the wake …

Skin appearance is essential for self‐esteem and quality of life; consequently, skin care
products represent a huge market. In particular, cosmeceuticals constitute a hybrid category …

Melatonin is synthesized by several tissues besides the pineal gland, and beyond its
regulatory effects in light‐dark cycle, melatonin is a hormone with neuroprotective, anti …

Monoamine oxidase B (MAO-B) metabolizes dopamine and plays an important role in
oxidative stress by altering the redox state of neuronal and glial cells. MAO-B inhibitors are a …