Background Pain in the neonate is associated with acute behavioural and physiological
changes. Cumulative pain is associated with morbidities, including adverse …

A broad range of evidence regarding the functional organization of the vertebrate brain–
spanning from comparative neurology to experimental psychology and neurophysiology to …

Objective: Inadequate assessment of pain in premature infants is a persistent clinical
problem. The objective of this research was to develop and validate a measure for …

Widespread acceptance of a definition of pain that focUseson pain perceptionhas led,
directlyor indirectly, to many recent advances. Important classificationsof pain syndromes …

The impact of invasive procedures on preterm neonates has received little systematic
attention. We examined facial activity, body movements, and physiological measures in 56 …

Clinical and laboratory investigations of neonatal pain suggest that preterm neonates have
an increased sensitivity to pain and that acute painful stimuli lead to the development of …

Acute pain is a highly complex, dynamic, subjective experience that is useful to growing
children, serving to warn them of danger and limiting exposure to additional injury. Children …

BACKGROUND: Neonates in a neonatal intensive care unit are exposed to a high number
of painful procedures. Since repeated and sustained pain can have consequences for the …

Objectives: To assess and compare the analgesic effects of orally administered glucose and
sucrose and pacifiers. To determine the synergistic analgesic effect of sucrose and pacifiers …

Many changes have taken place in pediatric pain management since the undertreatment of
children's pain was first reported. Notable advances include an increase in understanding …