Illuminating dendritic function with computational models
P Poirazi, A Papoutsi - Nature reviews neuroscience, 2020 - nature.com
Dendrites have always fascinated researchers: from the artistic drawings by Ramon y Cajal
to the beautiful recordings of today, neuroscientists have been striving to unravel the …
to the beautiful recordings of today, neuroscientists have been striving to unravel the …
Circuit investigations with open-source miniaturized microscopes: past, present and future
D Aharoni, TM Hoogland - Frontiers in cellular neuroscience, 2019 - frontiersin.org
The ability to simultaneously image the spatiotemporal activity signatures from many
neurons during unrestrained vertebrate behaviors has become possible through the …
neurons during unrestrained vertebrate behaviors has become possible through the …
The brain in motion: How ensemble fluidity drives memory-updating and flexibility
W Mau, ME Hasselmo, DJ Cai - Elife, 2020 - elifesciences.org
While memories are often thought of as flashbacks to a previous experience, they do not
simply conserve veridical representations of the past but must continually integrate new …
simply conserve veridical representations of the past but must continually integrate new …
NINscope, a versatile miniscope for multi-region circuit investigations
A de Groot, BJG van den Boom, RM van Genderen… - Elife, 2020 - elifesciences.org
Miniaturized fluorescence microscopes (miniscopes) have been instrumental to monitor
neural signals during unrestrained behavior and their open-source versions have made …
neural signals during unrestrained behavior and their open-source versions have made …
Miniscope-LFOV: a large-field-of-view, single-cell-resolution, miniature microscope for wired and wire-free imaging of neural dynamics in freely behaving animals
Imaging large-population, single-cell fluorescent dynamics in freely behaving animals larger
than mice remains a key endeavor of neuroscience. We present a large-field-of-view open …
than mice remains a key endeavor of neuroscience. We present a large-field-of-view open …
ezTrack: An open-source video analysis pipeline for the investigation of animal behavior
Tracking animal behavior by video is one of the most common tasks in the life sciences.
Although commercial software exists for executing this task, they often present enormous …
Although commercial software exists for executing this task, they often present enormous …
A stable hippocampal code in freely flying bats
Neural activity in the hippocampus is known to reflect how animals move through an
environment,. Although navigational behaviour may show considerable stability,,–, the …
environment,. Although navigational behaviour may show considerable stability,,–, the …
A deep-learning approach for online cell identification and trace extraction in functional two-photon calcium imaging
L Sità, M Brondi, P Lagomarsino de Leon Roig… - Nature …, 2022 - nature.com
In vivo two-photon calcium imaging is a powerful approach in neuroscience. However,
processing two-photon calcium imaging data is computationally intensive and time …
processing two-photon calcium imaging data is computationally intensive and time …
Modulation of brain hyperexcitability: potential new therapeutic approaches in Alzheimer's disease
People with Alzheimer's disease (AD) have significantly higher rates of subclinical and overt
epileptiform activity. In animal models, oligomeric Aβ amyloid is able to induce neuronal …
epileptiform activity. In animal models, oligomeric Aβ amyloid is able to induce neuronal …
BehaviorDEPOT is a simple, flexible tool for automated behavioral detection based on markerless pose tracking
Quantitative descriptions of animal behavior are essential to study the neural substrates of
cognitive and emotional processes. Analyses of naturalistic behaviors are often performed …
cognitive and emotional processes. Analyses of naturalistic behaviors are often performed …