Branched chain amino acids (BCAAs) are building blocks for all life-forms. We review here
the fundamentals of BCAA metabolism in mammalian physiology. Decades of studies have …

Branched chain amino acids (BCAAs), including leucine (Leu), isoleucine (Ile), and valine
(Val), play critical roles in the regulation of energy homeostasis, nutrition metabolism, gut …

Skeletal muscle supports locomotion and serves as the largest site of postprandial glucose
disposal; thus it is a critical organ for physical and metabolic health. Skeletal muscle mass is …

Leucine (Leu) is a nutritionally essential branched-chain amino acid (BCAA) in animal
nutrition. It is usually one of the most abundant amino acids in high-quality protein foods …

Background: Leucine is a key amino acid involved in the regulation of skeletal muscle
protein synthesis. Objective: We assessed the effect of the supplementation of a lower …

This study was designed to evaluate the effects of enriching an essential amino acid (EAA)
mixture with leucine on muscle protein metabolism in elderly and young individuals. Four (2 …

BCAAs stimulate protein synthesis in in vitro preparations of skeletal muscle. Likewise, the
stimulation of protein synthesis in skeletal muscle produced by intake of a mixed meal is due …

Resistance exercise is a potent stimulator of muscle protein synthesis and muscle cell
growth, with the increase in protein synthesis being detected within 2–3 h post‐exercise and …

Protein supplementation during resistance exercise training augments hypertrophic gains.
Protein ingestion and the resultant hyperaminoacidemia provides the building blocks …

The present study was designed to assess the effects of dietary leucine supplementation on
muscle protein synthesis and whole body protein kinetics in elderly individuals. Twenty …