Molecular mechanism of lncRNAs in pathogenesis and diagnosis of auto-immune diseases, with a special focus on lncRNA-based therapeutic approaches
Autoimmune diseases are a diverse set of conditions defined by organ damage due to
abnormal innate and acquired immune system responses. The pathophysiology of …
abnormal innate and acquired immune system responses. The pathophysiology of …
Translation of cell therapies to treat autoimmune disorders
Autoimmune diseases are a diverse and complex set of chronic disorders with a substantial
impact on patient quality of life and a significant global healthcare burden. Current …
impact on patient quality of life and a significant global healthcare burden. Current …
Regulatory T Cells and Their Derived Cell Pharmaceuticals as Emerging Therapeutics Against Autoimmune Diseases
L Yu, Y Fu, R Miao, J Cao, F Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Caused by the loss in the tolerance against self‐antigens, autoimmune diseases are chronic
disorders that impact millions of individuals annually with significant economic burden. They …
disorders that impact millions of individuals annually with significant economic burden. They …
Genetic and Epigenetic Association of FOXP3 with Papillary Thyroid Cancer Predisposition
Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy with an
increased female incidence ratio. The specific traits of X chromosome inheritance may be …
increased female incidence ratio. The specific traits of X chromosome inheritance may be …
Causal associations of immune cell phenotypes with migraine: A mendelian randomization study
W Chai, W Chai, F Guo - Molecular Pain, 2024 - journals.sagepub.com
The interaction between the immune system and the brain, crucial for blood–brain barrier
integrity, is a potential factor in migraine development. Although there's evidence of a …
integrity, is a potential factor in migraine development. Although there's evidence of a …
[HTML][HTML] Interleukin-38-overexpressing adenovirus infection in dendritic cell-based treatment enhances immunotherapy for allergic asthma via inducing Foxp3+ …
HC Chuang, JH Chang, YY Fan, CL Hsieh… - Biomedicine & …, 2024 - Elsevier
Allergic asthma is a chronic disease tied to unusual immune reactions involving type 2 T
helper (Th2) cells specific to allergens. Dendritic cells (DCs) play a crucial role in guiding T …
helper (Th2) cells specific to allergens. Dendritic cells (DCs) play a crucial role in guiding T …
[HTML][HTML] Oral squamous cell carcinomas drive monocytes into immunosuppressive CD25+ CD163+ CD206+ macrophages
HF Pelaez-Prestel, F Gonzalez-Martin, A Ras-Carmona… - Oral Oncology, 2024 - Elsevier
Tumor-associated macrophages (TAMs) are major cellular components in the tumor
microenvironment of oral squamous cell carcinomas (OSCCs). Most of these TAMs derive …
microenvironment of oral squamous cell carcinomas (OSCCs). Most of these TAMs derive …
[HTML][HTML] Biomaterial-enhanced treg cell immunotherapy: A promising approach for transplant medicine and autoimmune disease treatment
Regulatory T cells (Tregs) are crucial for preserving tolerance in the body, rendering Treg
immunotherapy a promising treatment option for both organ transplants and autoimmune …
immunotherapy a promising treatment option for both organ transplants and autoimmune …
Intestinal flora: a potential pathogenesis mechanism and treatment strategy for type 1 diabetes mellitus
S Huang, F Li, C Quan, D Jin - Gut Microbes, 2024 - Taylor & Francis
Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease characterized by
destruction of pancreatic β-cells, leading to insulin deficiency and hyperglycemia, and its …
destruction of pancreatic β-cells, leading to insulin deficiency and hyperglycemia, and its …
An updated overview of the application of CAR‐T cell therapy in neurological diseases
H Shahabifard, M Zarei, K Kookli… - Biotechnology …, 2023 - Wiley Online Library
Genetically modified immune cells, especially CAR‐T cells, have captured the attention of
scientists over the past 10 years. In the fight against cancer, these cells have a special place …
scientists over the past 10 years. In the fight against cancer, these cells have a special place …