IL-6 is involved both in immune responses and in inflammation, hematopoiesis, bone
metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely …

Breast cancer is the most commonly diagnosed cancer in women. Metastasis is the primary
cause of mortality for breast cancer patients. Multiple mechanisms underlie breast cancer …

Since the molecular cloning of interleukin-6 (IL-6) in 1986, many other cytokines have been
found to share the same signal transducer, gp130, in their receptor complexes. Thus, the IL …

Interleukin-6 (IL-6) is a pleiotropic cytokine that not only regulates the immune and
inflammatory response but also affects hematopoiesis, metabolism, and organ development …

Cytokines of the transforming growth factor β (TGF-β) family, including TGF-βs, bone
morphogenic proteins (BMPs), activins, and Nodal, play crucial roles in embryonic …

The cytokine interleukin‐31 has been implicated in the pathophysiology of multiple atopic
disorders such as atopic dermatitis (AD), allergic rhinitis, and airway hyper‐reactivity. In AD …

Abstract Interleukin-6 (IL-6) is one of the most important inflammatory cytokines. IL-6 is
unique in signaling via a membrane bound and a soluble receptor. Intriguingly, these two …

Signal transducers and activators of transcription (STATs) comprise a family of cytoplasmic
transcription factors that mediate intracellular signaling that is usually generated at cell …

Autophagy is an evolutionarily conserved process in eukaryotes that eliminates harmful
components and maintains cellular homeostasis in response to a series of extracellular …

Introduction Mesenchymal stem cell-conditioned medium (MSC-CM) has been shown to
have protective effects against various cellular-injury models. This mechanism of protection …