The dual role of HLA-C in tolerance and immunity at the maternal-fetal interface

H Papúchová, TB Meissner, Q Li… - Frontiers in …, 2019 - frontiersin.org
To establish a healthy pregnancy, maternal immune cells must tolerate fetal allo-antigens
and remain competent to respond to infections both systemically and in placental tissues …

Natural killer cell education in human health and disease

JE Boudreau, KC Hsu - Current opinion in immunology, 2018 - Elsevier
Highlights•NK cell education is endowed by independently-segregating polygenic KIR and
HLA which, combined, enable diverse effector functions.•Education counterbalances each …

[HTML][HTML] From hepatitis C virus infection to B-cell lymphoma

L Couronné, E Bachy, S Roulland, B Nadel, F Davi… - Annals of …, 2018 - Elsevier
In addition to liver disorders, hepatitis C virus (HCV) is also associated with extrahepatic
immune manifestations and B-cell non-Hodgkin lymphoma (NHL), especially marginal zone …

Radiomics and machine learning analysis by computed tomography and magnetic resonance imaging in colorectal liver metastases prognostic assessment

V Granata, R Fusco, F De Muzio, MC Brunese… - La radiologia …, 2023 - Springer
Objective The aim of this study was the evaluation radiomics analysis efficacy performed
using computed tomography (CT) and magnetic resonance imaging in the prediction of …

Expression of KIR2DS1 by decidual natural killer cells increases their ability to control placental HCMV infection

ÂC Crespo, JL Strominger… - Proceedings of the …, 2016 - National Acad Sciences
The combination of the activating killer cell Ig-like receptor 2DS1 (KIR2DS1) expressed by
maternal decidual natural killer cells (dNK) and the presence of its ligand, the HLA-C …

Serum and tissue markers in hepatocellular carcinoma and cholangiocarcinoma: clinical and prognostic implications

M Berretta, C Cavaliere, L Alessandrini… - …, 2016 - pmc.ncbi.nlm.nih.gov
HCC represents the sixth most common cancer worldwide and the second leading cause of
cancer-related death. Despite the high incidence, treatment options for advanced HCC …

Risk assessment and pancreatic cancer: Diagnostic management and artificial intelligence

V Granata, R Fusco, SV Setola, R Galdiero… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic cancer (PC) is one of the deadliest cancers. Its high mortality
rate is correlated with several explanations; the main one is the late disease stage at which …

[HTML][HTML] Maternal natural killer cells at the intersection between reproduction and mucosal immunity

EV Shmeleva, F Colucci - Mucosal Immunology, 2021 - Elsevier
Many maternal immune cells populate the decidua, which is the mucosal lining of the uterus
transformed during pregnancy. Here, abundant natural killer (NK) cells and macrophages …

[HTML][HTML] An immunogenetic view of COVID-19

VRC Aguiar, DG Augusto, EC Castelli… - … and Molecular Biology, 2021 - SciELO Brasil
Meeting the challenges brought by the COVID-19 pandemic requires an interdisciplinary
approach. In this context, integrating knowledge of immune function with an understanding …

Genetic factors that affect spontaneous clearance of hepatitis C or B virus, response to treatment, and disease progression

TR O'Brien, HI Yang, S Groover, WJ Jeng - Gastroenterology, 2019 - Elsevier
Hepatitis C virus (HCV) and hepatitis B virus (HBV) infections can lead to cirrhosis, end-
stage liver disease, and hepatocellular carcinoma. Over the past decade, studies of …