Outdoor air pollution is one of the leading contributors to adverse respiratory health
outcomes in urban areas around the world. Children are highly sensitive to the adverse …

Childhood obesity rates have dramatically risen in numerous countries worldwide. Obesity is
likely a factor in increased asthma risk, which is already one of the most widespread chronic …

BACKGROUND: Inducible nitric oxide synthase (iNOS; encoded by nitric oxide synthase
isoform 2 [NOS2]) is the major enzyme for nitric oxide synthesis in airways. As such …

We assessed the effect of daily variations in ambient air pollutants on exhaled nitric oxide
fraction (F eNO) using data from a cohort of school children with large differences in air …

Asthma-like symptoms like wheezing and dyspnea affect 1 in every 3 preschool children. An
easily available biomarker that predicts later asthma or unfavorable lung growth in these …

Rationale: Genetic variation in arginase (ARG) and nitric oxide synthase (NOS) has been
associated with exhaled nitric oxide (FeNO) levels in children. Little is known about whether …

Nitric oxide (NO) is endogenously released in the airways, and the fractional concentration
of NO in exhaled breath (FeNO) is now recognized as a surrogate marker of eosinophilic …

Introduction: Obesity affects about 40% of US adults and 18% of children. Its impact on the
pulmonary system is best described for asthma. Areas covered: We reviewed the literature …

Background and Objectives: Measurement of fractional exhaled nitric oxide (FeNO)
concentration is currently used as a non-invasive biomarker to assess airway inflammation …

Background: The measurement of the exhaled nitric oxide fraction (FE NO) is proposed as a
useful marker of airway inflammation. In healthy adults, there have been a few studies of the …