Polyploids—organisms that have multiple sets of chromosomes—are common in certain
plant and animal taxa, and can be surprisingly stable. The evidence that has emerged from …

▪ Abstract Over 35 years ago, Susumu Ohno stated that gene duplication was the single
most important factor in evolution. He reiterated this point a few years later in proposing that …

The hypothesis that the relatively large and complex vertebrate genome was created by two
ancient, whole genome duplications has been hotly debated, but remains unresolved. We …

Identifying the mechanisms of eukaryotic genome evolution by comparative genomics is
often complicated by the multiplicity of events that have taken place throughout the history of …

One of the most pervasive challenges in molecular phylogenetics is the incongruence
between phylogenies obtained using different data sets, such as individual genes. To …

Whole-genome duplication followed by massive gene loss and specialization has long been
postulated as a powerful mechanism of evolutionary innovation. Recently, it has become …

It is often anticipated that many of today's diploid plant species are in fact paleopolyploids.
Given that an ancient large-scale duplication will result in an excess of relatively old …

To study the evolutionary effects of polyploidy on plant gene functions, we analyzed
functional genomics data for a large number of duplicated gene pairs formed by ancient …

We have identified 242 Anopheles gambiae genes from 18 gene families implicated in
innate immunity and have detected marked diversification relative to Drosophila …

We developed the Yeast Gene Order Browser (YGOB; http://wolfe. gen. tcd. ie/ygob) to
facilitate visual comparisons and computational analysis of synteny relationships in yeasts …