Mechanistic understanding from molecular dynamics in pharmaceutical research 2: lipid membrane in drug design

T Róg, M Girych, A Bunker - Pharmaceuticals, 2021 - mdpi.com
We review the use of molecular dynamics (MD) simulation as a drug design tool in the
context of the role that the lipid membrane can play in drug action, ie, the interaction …

QCM sensor arrays, electroanalytical techniques and NIR spectroscopy coupled to multivariate analysis for quality assessment of food products, raw materials …

DK Bwambok, N Siraj, S Macchi, NE Larm, GA Baker… - Sensors, 2020 - mdpi.com
Quality checks, assessments, and the assurance of food products, raw materials, and food
ingredients is critically important to ensure the safeguard of foods of high quality for safety …

Selective advantages of synapses in evolution

LL Moroz, DY Romanova - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
The common ancestor of all Metazoa (Urmetazoan) was a nerveless animal (Mackie, 1970,
1990; Moroz, 2009). This hypothetical Urmetazoan likely used electrical and chemical …

Surface plasmon resonance monitoring of mono-rhamnolipid interaction with phospholipid-based liposomes

M Belkilani, M Shokouhi, C Farre, Y Chevalier, S Minot… - Langmuir, 2021 - ACS Publications
The interactions of mono-rhamnolipids (mono-RLs) with model membranes were
investigated through a biomimetic approach using phospholipid-based liposomes …

Facile electrochemical demethylation of 2-methoxyphenol to surface-confined catechol on the MWCNT and its efficient electrocatalytic hydrazine oxidation and …

M Gandhi, D Rajagopal, A Senthil Kumar - ACS omega, 2020 - ACS Publications
Owing to its biological significance, preparation of stable surface-confined catechol (CA) is a
long-standing interest in electrochemistry and surface chemistry. In this connection, various …

Synthesis and validation of a bioinspired catechol-functionalized Pt (IV) prodrug for preclinical intranasal glioblastoma treatment

X Mao, S Wu, P Calero-Pérez, AP Candiota, P Alfonso… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma (GB) is a type of brain cancer with a poor prognosis and few
improvements in its treatment. One of the greatest difficulties in GB therapy lies in the fact …

Membrane bound catechol-O-methytransferase is the dominant isoform for dopamine metabolism in PC12 cells and rat brain

Y Su, M DePasquale, G Liao, I Buchler, G Zhang… - European journal of …, 2021 - Elsevier
Impaired dopamine activity in the dorsolateral prefrontal cortex (DLPFC) is thought to
contribute to cognitive deficits in diseases such as schizophrenia, attention deficit …

BALM: Watching the Formation of Tethered Bilayer Lipid Membranes with submicron lateral resolution

J Bompard, O Maniti, R Aboukhachfe, D Ausserre… - Langmuir, 2021 - ACS Publications
Tethered bilayer lipid membranes (tBLMs) are artificial membranes largely used for the in
situ study of biological membranes and membrane-associated proteins. To date, the …

Highly stable scalable production of porous graphene-polydopamine nanocomposites for drug molecule sensing

X Ding, R Chen, J Xu, J Hu, Z Zhao, C Zhang, L Zheng… - Talanta, 2025 - Elsevier
As atenolol overdosing can lead to severe health complications, the rapid detection of
atenolol intake in point-of-care settings is highly desirable. The recent advancement of redox …

Interaction of Dopamine with zwitterionic DMPC and anionic DMPS multilamellar vesicle membranes

AK Sahu, AK Mishra - Langmuir, 2021 - ACS Publications
Dopamine (DA), a naturally occurring neurotransmitter, plays a crucial role in the function of
the mammalian nervous system. DA–lipid-membrane interaction is inevitable during the …