Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

DNAzyme-mediated assays for amplified detection of nucleic acids and proteins

H Peng, AM Newbigging, Z Wang, J Tao… - Analytical …, 2018 - ACS Publications
DNAzymes have several practical advantages when compared to protein enzymes and
ribozymes and thus have been extensively used for developing analytical techniques. 6− 18 …

Next-Generation in Situ Hybridization Chain Reaction: Higher Gain, Lower Cost, Greater Durability

HMT Choi, VA Beck, NA Pierce - ACS nano, 2014 - ACS Publications
Hybridization chain reaction (HCR) provides multiplexed, isothermal, enzyme-free,
molecular signal amplification in diverse settings. Within intact vertebrate embryos, where …

DNAzyme-based biosensors and nanodevices

L Gong, Z Zhao, YF Lv, SY Huan, T Fu… - Chemical …, 2015 - pubs.rsc.org
DNAzymes, screened through in vitro selection, have shown great promise as molecular
tools in the design of biosensors and nanodevices. The catalytic activities of DNAzymes …

Label-free electrochemical immunosensor based on flower-like Ag/MoS2/rGO nanocomposites for ultrasensitive detection of carcinoembryonic antigen

Y Wang, Y Wang, D Wu, H Ma, Y Zhang, D Fan… - Sensors and Actuators B …, 2018 - Elsevier
In this work, a label-free electrochemical immunosensor was developed for the quantitative
detection of carcinoembryonic antigen (CEA). Flower-like Ag/MoS 2/rGO nanocomposites …

Magnetic bead-based reverse colorimetric immunoassay strategy for sensing biomolecules

Z Gao, M Xu, L Hou, G Chen, D Tang - Analytical Chemistry, 2013 - ACS Publications
A novel reverse colorimetric immunoassay (RCIA) strategy was for the first time designed
and utilized for sensitive detection of low-abundance protein (prostate-specific antigen, PSA …

Magnetic-assisted methylene blue-intercalated amplified dsDNA for polarity-switching-mode photoelectrochemical aptasensing

F Mo, M Han, X Weng, Y Zhang, J Li, H Li - Analytical Chemistry, 2020 - ACS Publications
Organic dyes are typically applied as photosensitizers in photoelectrochemical (PEC) cells
but have not been reported in polarity-reversal-mode PEC sensors with excellent sensitivity …

An electrochemical biosensor for SARS-CoV-2 detection via its papain-like cysteine protease and the protease inhibitor screening

Q Liang, Y Huang, M Wang, D Kuang, J Yang… - Chemical Engineering …, 2023 - Elsevier
The persistent coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) is still infecting hundreds of thousands of …

Ti3C2 MXene nanosheet-based capacitance immunoassay with tyramine-enzyme repeats to detect prostate-specific antigen on interdigitated micro-comb electrode

J Chen, P Tong, L Huang, Z Yu, D Tang - Electrochimica Acta, 2019 - Elsevier
An interdigitated capacitance immunosensing system based enzymatic biocatalytic
precipitation on micro-comb electrode was designed for the sensitive detection of prostate …

Recent advances in enhancement strategies for electrochemical ELISA-based immunoassays for cancer biomarker detection

SK Arya, P Estrela - Sensors, 2018 - mdpi.com
Electrochemical enzyme-linked immunosorbent assay (ELISA)-based immunoassays for
cancer biomarker detection have recently attracted much interest owing to their higher …