The evolving translational potential of small extracellular vesicles in cancer
Cancer-derived extracellular vesicles (EVs) are regarded as having promising potential to
be used as therapeutics and disease biomarkers. Mechanistically, EVs have been shown to …
be used as therapeutics and disease biomarkers. Mechanistically, EVs have been shown to …
[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics
A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …
[HTML][HTML] Exosome-mediated metastasis: communication from a distance
Metastasis, a critical phase of tumor progression, remains a primary challenge in treating
cancer and a major cause of cancer mortality. Cell-cell communication via extracellular …
cancer and a major cause of cancer mortality. Cell-cell communication via extracellular …
[HTML][HTML] RGD-binding integrins revisited: how recently discovered functions and novel synthetic ligands (re-) shape an ever-evolving field
Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …
investigated as therapeutic targets over the last decades, motivated by their multiple …
[HTML][HTML] Exosomes in cancer: small particle, big player
X Zhang, X Yuan, H Shi, L Wu, H Qian, W Xu - Journal of hematology & …, 2015 - Springer
Exosomes have emerged as a novel mode of intercellular communication. Exosomes can
shuttle bioactive molecules including proteins, DNA, mRNA, as well as non-coding RNAs …
shuttle bioactive molecules including proteins, DNA, mRNA, as well as non-coding RNAs …
Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds
AA Farooqi, NN Desai, MZ Qureshi… - Biotechnology …, 2018 - Elsevier
A rapidly growing body of experimental evidence has begun to shed light on the wide
ranging molecular mechanisms which modulate intra-and inter-cellular communications. A …
ranging molecular mechanisms which modulate intra-and inter-cellular communications. A …
[HTML][HTML] The origin and functions of exosomes in cancer
C Rajagopal, KB Harikumar - Frontiers in oncology, 2018 - frontiersin.org
Exosomes are nanovesicles having a maximum size of 150 nm and is a newly emerging
focus in various fields of research. Its role in cargo trafficking along with its differential …
focus in various fields of research. Its role in cargo trafficking along with its differential …
[HTML][HTML] The role of tumor microenvironment in therapeutic resistance
Cancer cells undergo unlimited progression and survival owing to activation of oncogenes.
However, support of the tumor microenvironment is essential to the formation of clinically …
However, support of the tumor microenvironment is essential to the formation of clinically …
Extracellular vesicles exploit viral entry routes for cargo delivery
HM Van Dongen, N Masoumi, KW Witwer… - Microbiology and …, 2016 - Am Soc Microbiol
Extracellular vesicles (EVs) have emerged as crucial mediators of intercellular
communication, being involved in a wide array of key biological processes. Eukaryotic cells …
communication, being involved in a wide array of key biological processes. Eukaryotic cells …
[HTML][HTML] Extracellular vesicles: Critical players during cell migration
Cell migration is essential for the development and maintenance of multicellular organisms,
contributing to embryogenesis, wound healing, immune response, and other critical …
contributing to embryogenesis, wound healing, immune response, and other critical …