Recent progress and trends in X-ray-induced photodynamic therapy with low radiation doses

L He, X Yu, W Li - ACS nano, 2022 - ACS Publications
The prominence of photodynamic therapy (PDT) in treating superficial skin cancer inspires
innovative solutions for its congenitally deficient shadow penetration of the visible-light …

Acridine orange: a review of novel applications for surgical cancer imaging and therapy

VA Byvaltsev, LA Bardonova, NR Onaka… - Frontiers in …, 2019 - frontiersin.org
Introduction: Acridine orange (AO) was first extracted from coal tar in the late nineteenth
century and was used as a fluorescent dye. In this paper, we review emergent research …

Microenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy

S Fais, G Venturi, B Gatenby - Cancer and Metastasis Reviews, 2014 - Springer
Much effort is currently devoted to developing patient-specific cancer therapy based on
molecular characterization of tumors. In particular, this approach seeks to identify driver …

Using X-rays in photodynamic therapy: an overview

L Larue, AB Mihoub, Z Youssef, L Colombeau… - Photochemical & …, 2018 - pubs.rsc.org
Photodynamic therapy is a therapeutic option to treat cancer and other diseases. PDT is
used every day in dermatology, and recent developments in the treatment of glioblastoma …

Acridine Orange/exosomes increase the delivery and the effectiveness of Acridine Orange in human melanoma cells: A new prototype for theranostics of tumors

E Iessi, M Logozzi, L Lugini, T Azzarito… - Journal of Enzyme …, 2017 - Taylor & Francis
Specifically targeted drug delivery systems with low immunogenicity and toxicity are deemed
to increase efficacy of cancer chemotherapy. Acridine Orange (AO) is an acidophilic dye with …

Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents

M Dichiara, O Prezzavento, A Marrazzo, V Pittala… - European Journal of …, 2017 - Elsevier
In the search of novel strategies for the treatment of cancer, photodynamic therapy (PDT)
has emerged as an effective, safe for repeated use, and non-invasive method. This …

Physiological roles of chloride ions in bodily and cellular functions

Y Marunaka - The Journal of Physiological Sciences, 2023 - Springer
Physiological roles of Cl−, a major anion in the body, are not well known compared with
those of cations. This review article introduces:(1) roles of Cl− in bodily and cellular …

[HTML][HTML] The safety and efficiency of photodynamic therapy for the treatment of osteosarcoma: A systematic review of in vitro experiment and animal model reports

G Tan, J Xu, Q Yu, Z Yang, H Zhang - Photodiagnosis and photodynamic …, 2022 - Elsevier
Background Osteosarcoma (OS) is an aggressive malignant bone tumour with high
mortality. A poor prognosis is noted in patients with distal metastases or multidrug …

Natural extracellular nanovesicles and photodynamic molecules: is there a future for drug delivery?

K Kusuzaki, T Matsubara, H Murata… - Journal of enzyme …, 2017 - Taylor & Francis
Photodynamic molecules represent an alternative approach for cancer therapy for their
property (i) to be photo-reactive;(ii) to be not-toxic for target cells in absence of light;(iii) to …

DNA templated Click Chemistry via 5-vinyl-2′-deoxyuridine and an acridine-tetrazine conjugate induces DNA damage and apoptosis in cancer cells

Y Li, Y Ling, MO Loehr, S Chaabane, OW Cheng… - Life Sciences, 2023 - Elsevier
Abstract Aims Click Chemistry is providing valuable tools to biomedical research, but its
direct use in therapies remains nearly unexplored. For cancer treatment, nucleoside …