Oncolytic virotherapy is an emerging treatment modality that uses replication-competent
viruses to destroy cancers. Recent advances include preclinical proof of feasibility for a …

Early-stage clinical trials of oncolytic virotherapy have reported the safety of several virus
platforms, and viruses from three families have progressed to advanced efficacy trials. In …

To protect against the harmful consequences of viral infections, organisms are equipped
with sophisticated antiviral mechanisms, including cell‐intrinsic means to restrict viral …

Oncolytic virus (OV) therapy is an emerging anti-cancer approach that utilizes viruses to
preferentially infect and kill cancer cells, while not harming healthy cells. Vesicular stomatitis …

Oncolytic virotherapy relies on the administration of non-pathogenic viral strains that
selectively infect and kill malignant cells while favoring the elicitation of a therapeutically …

Patients with relapsed acute myeloid leukemia (AML) have limited therapeutic options.
Vesicular stomatitis virus (VSV)–interferon β (IFNβ)–sodium iodide symporter (NIS) is an …

Introduction Vesicular stomatitis virus (VSV) has long been a useful research tool in virology
and recently become an essential part of medicinal products. Vesiculovirus research is …

Vesicular stomatitis virus (VSV) is a prototypic nonsegmented negative-strand RNA virus.
VSV's broad cell tropism makes it a popular model virus for many basic research …

Oncolytic viruses are natural or genetically modified viral species that selectively infect and
kill neoplastic cells. Such an innate or exogenously conferred specificity has generated …

As cancer treatment tools, oncolytic viruses (OV) have yet to realize what some see as their
ultimate clinical potential. In this study, we have engineered a chimeric vesicular stomatitis …