[HTML][HTML] Systemic inflammation in colorectal cancer: Underlying factors, effects, and prognostic significance
AE Tuomisto, MJ Mäkinen… - World journal of …, 2019 - ncbi.nlm.nih.gov
Systemic inflammation is a marker of poor prognosis preoperatively present in around 20%-
40% of colorectal cancer patients. The hallmarks of systemic inflammation include an …
40% of colorectal cancer patients. The hallmarks of systemic inflammation include an …
Periostin: a matricellular protein with multiple functions in cancer development and progression
L González-González, J Alonso - Frontiers in oncology, 2018 - frontiersin.org
Tumor microenvironment is considered nowadays as one of the main players in cancer
development and progression. Tumor microenvironment is highly complex and consists of …
development and progression. Tumor microenvironment is highly complex and consists of …
Therapeutic ablation of gain-of-function mutant p53 in colorectal cancer inhibits Stat3-mediated tumor growth and invasion
R Schulz-Heddergott, N Stark, SJ Edmunds, J Li… - Cancer Cell, 2018 - cell.com
Over half of colorectal cancers (CRCs) harbor TP53 missense mutations (mutp53). We show
that the most common mutp53 allele R248Q (p53 Q) exerts gain of function (GOF) and …
that the most common mutp53 allele R248Q (p53 Q) exerts gain of function (GOF) and …
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients
G Jia, RW Erickson, DF Choy, S Mosesova… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Eosinophilic airway inflammation is heterogeneous in asthmatic patients.
We recently described a distinct subtype of asthma defined by the expression of genes …
We recently described a distinct subtype of asthma defined by the expression of genes …
Periostin: biology and function in cancer
Periostin (POSTN), a member of the matricellular protein family, is a secreted adhesion-
related protein produced in the periosteum and periodontal ligaments. Matricellular proteins …
related protein produced in the periosteum and periodontal ligaments. Matricellular proteins …
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver
Background Colorectal cancer is the third most frequently diagnosed cancer and the third
cause of cancer deaths in the United States. Despite the fact that tumor cell-intrinsic …
cause of cancer deaths in the United States. Despite the fact that tumor cell-intrinsic …
A proteomics platform combining depletion, multi-lectin affinity chromatography (M-LAC), and isoelectric focusing to study the breast cancer proteome
Z Zeng, M Hincapie, SJ Pitteri, S Hanash… - Analytical …, 2011 - ACS Publications
The discovery of breast cancer associated plasma/serum biomarkers is important for early
diagnosis, disease mechanism elucidation, and determination of treatment strategy for the …
diagnosis, disease mechanism elucidation, and determination of treatment strategy for the …
The role of periostin in angiogenesis and lymphangiogenesis in tumors
A Wasik, K Ratajczak-Wielgomas, A Badzinski… - Cancers, 2022 - mdpi.com
Simple Summary Cancers are common diseases that affect people of all ages worldwide.
For this reason, continuous attempts are being made to improve current therapeutic options …
For this reason, continuous attempts are being made to improve current therapeutic options …
Fibroblast activation and abnormal extracellular matrix remodelling as common hallmarks in three cancer‐prone genodermatoses
Background Recessive dystrophic epidermolysis bullosa (RDEB), Kindler syndrome (KS)
and xeroderma pigmentosum complementation group C (XPC) are three cancer‐prone …
and xeroderma pigmentosum complementation group C (XPC) are three cancer‐prone …
Renal fibrosis: recent translational aspects
H François, C Chatziantoniou - Matrix Biology, 2018 - Elsevier
Renal fibrogenesis is the common final pathway to all renal injuries that consequently leads
to Chronic Kidney Disease (CKD). Renal fibrogenesis corresponds to the replacement of …
to Chronic Kidney Disease (CKD). Renal fibrogenesis corresponds to the replacement of …