Role of resveratrol in the management of insulin resistance and related conditions: Mechanism of action

E Abbasi Oshaghi, MT Goodarzi… - Critical reviews in …, 2017 - Taylor & Francis
Abstract Resveratrol (RES), a well-known antioxidant, is present in numerous plant species
and, as a result, is easily obtained through dietary intake of plant-based foods and …

Improved glucose homeostasis in obese mice treated with resveratrol is associated with alterations in the gut microbiome

MM Sung, TT Kim, E Denou, CLM Soltys, SM Hamza… - Diabetes, 2017 - Am Diabetes Assoc
Oral administration of resveratrol is able to improve glucose homeostasis in obese
individuals. Herein we show that resveratrol ingestion produces taxonomic and predicted …

Are gut dysbiosis, barrier disruption, and endotoxemia related to adipose tissue dysfunction in metabolic disorders? Overview of the mechanisms involved

D Rosendo-Silva, S Viana, E Carvalho, F Reis… - Internal and Emergency …, 2023 - Springer
Recently, compelling evidence points to dysbiosis and disruption of the epithelial intestinal
barrier as major players in the pathophysiology of metabolic disorders, such as obesity …

Beta-1 and not beta-3 adrenergic receptors may be the primary regulator of human brown adipocyte metabolism

MJ Riis-Vestergaard, B Richelsen… - The Journal of …, 2020 - academic.oup.com
Purpose Brown adipose tissue (BAT) activation in humans has gained interest as a potential
target for treatment of obesity and insulin resistance. In rodents, BAT is primarily induced …

Antihyperglycemic effect of rice husk derived xylooligosaccharides in high‐fat diet and low‐dose streptozotocin‐induced type 2 diabetic rat model

N Khat‐udomkiri, P Toejing, S Sirilun… - Food science & …, 2020 - Wiley Online Library
Rice husk (RH) is an agricultural waste obtained from rice milling process. Our previous
study demonstrated the optimized process of extracting xylooligosaccharides (XOS), a …

Resveratrol as a potential protective compound against metabolic inflammation

H Ghahremani, A Bahramzadeh… - Acta Biochimica …, 2023 - publish.kne-publishing.com
Although the exact mechanism linking obesity to type 2 diabetes (T2D) remains unknown,
accumulating evidence suggests that low-grade chronic metabolic inflammation or …

Comprehensive metabolomic analysis in blood, urine, fat, and muscle in men with metabolic syndrome: A randomized, placebo-controlled clinical trial on the effects of …

AS Korsholm, TN Kjær, MJ Ornstrup… - International journal of …, 2017 - mdpi.com
Resveratrol possesses several beneficial metabolic effects in rodents, while the effects of
resveratrol in humans remain unclear. Therefore, we performed a non-targeted …

Sustained maternal inflammation during the early third-trimester yields intrauterine growth restriction, impaired skeletal muscle glucose metabolism, and diminished β …

CN Cadaret, EM Merrick, TL Barnes… - Journal of animal …, 2019 - academic.oup.com
Maternal inflammation causes fetal intrauterine growth restriction (IUGR), but its impact on
fetal metabolism is not known. Thus, our objective was to determine the impact of sustained …

Glucose metabolism in brown adipose tissue determined by deuterium metabolic imaging in rats

MJ Riis-Vestergaard, C Laustsen… - International journal of …, 2020 - nature.com
Abstract Background/Objectives Brown adipose tissue (BAT) has gained growing interest as
a potential target for treatment of obesity. Currently, the most widely used technique/method …

Inflammation downregulates UCP1 expression in brown adipocytes potentially via SIRT1 and DBC1 interaction

MK Nøhr, N Bobba, B Richelsen, S Lund… - International journal of …, 2017 - mdpi.com
Brown adipose tissue thermogenesis at the cost of energy is not only important for the
development of obesity, but also possesses great promise in anti-obesity treatment …