The past decade has witnessed an explosion of evidence suggesting that many
neurodegenerative diseases can be detected years, if not decades, earlier than previously …

Purpose This review assessed the psychological impact that acquiring personal and familial
genetic information has on children. We also examined the concordance between the …

Sociogenomics has rapidly become one of the trendiest sciences of the new millennium.
Practitioners view human nature and life outcomes as the result of genetic and social factors …

Objective To better understand the consequences of returning whole genome sequencing
(WGS) results in paediatrics and facilitate its evidence-based clinical implementation, we …

American Academy of Pediatrics (AAP) and American College of Medical Genetics (ACMG)
recently provided two recommendations about predictive genetic testing of children. The …

Purpose As advances in research have made a growing number of genetic tests available,
clinicians will increasingly be faced with making decisions about when offering genetic …

The present review analyses the implications of the best interests of the child principle,
which is one of the most widely discussed principles of medical ethics and human rights, for …

Predictive genetic testing is now routinely offered to asymptomatic adults at risk for genetic
disease. However, testing of minors at risk for adult-onset conditions, where no treatment or …

Genomic medicine offers a growing number of methods to diagnose, cure or prevent
disability. Although many disabled people welcome these advances, others have …

Aims: This study assessed parent knowledge of newborn screening (NBS) and parent
attitudes toward NBS for untreatable conditions, NBS for late-onset disorders and informed …