Biomineralization is the process by which organisms form mineralized tissues with
hierarchical structures and excellent properties, including the bones and teeth in …

Peptide amphiphiles are a class of molecules that combine the structural features of
amphiphilic surfactants with the functions of bioactive peptides and are known to assemble …

The principles of minimally invasive dentistry clearly dictate the need for clinically effective
measures to remineralize early enamel caries lesions. While fluoride-mediated …

We have used the pH-induced self-assembly of a peptide-amphiphile to make a
nanostructured fibrous scaffold reminiscent of extracellular matrix. The design of this peptide …

The study of biomineralization is not only important to gain an understanding of how mineral-
rich tissues are created in vivo but also because it is a great source of inspiration for the …

Living organisms are capable of inducing the crystallization and deposition of a wide variety
of minerals, 1 but the vertebrates mainly utilize the calcium phosphates in constructing their …

The current understanding of the relationships between cell shape, intracellular forces and
signaling, nuclear shape and organization, and gene expression is in its infancy. Here we …

The extracellular matrix (ECM) of bone and dentin contains several non-collagenous
proteins. One category of non-collagenous protein is termed the SIBLING (S mall I ntegrin-B …

Dentin sialophosphoprotein (Dspp) is mainly expressed in teeth by the odontoblasts and
preameloblasts. The Dspp mRNA is translated into a single protein, Dspp, and cleaved into …

The hereditary dentine disorders, dentinogenesis imperfecta (DGI) and dentine dysplasia
(DD), comprise a group of autosomal dominant genetic conditions characterised by …