Executive summary The past six decades have seen remarkable improvements in health
outcomes for people with cystic fibrosis, which was once a fatal disease of infants and young …

Developments in managing CF continue to drive dramatic improvements in survival. As
newborn screening rolls-out across Europe, CF centres are increasingly caring for cohorts of …

Specialised CF care has led to a dramatic improvement in survival in CF: in the last four
decades, well above what was seen in the general population over the same period. With …

Background Advanced cystic fibrosis lung disease (ACFLD) is common, is associated with
reduced quality of life, and remains the most frequent cause of death in individuals with …

Background: Advances in treatments for cystic fibrosis (CF) continue to extend survival. An
updated estimate of survival is needed for better prognostication and to anticipate evolving …

Rationale: People with cystic fibrosis (CF) experience acute worsening of respiratory
symptoms and lung function known as pulmonary exacerbations. Treatment with …

Cystic Fibrosis (CF) was the most common fatal single-gene disorder in Caucasians.
However, CF is found in non-Caucasians, including people of 100% African descent, and …

Cystic fibrosis (CF) is the most common autosomal recessive disorder in Caucasian
populations. Individuals with CF have seen significant increases in life expectancy in the last …

Background Cystic fibrosis related diabetes (CFRD) has implications for morbidity and
mortality with several risk factors identified. We studied the epidemiology of CFRD in the …

Several key advances have been made in the treatment and management of people with
cystic fibrosis in the past two decades. Substantial improvements in survival have resulted …