Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

Amphibians exhibit various, characteristic adaptations related to their “incomplete” shift from
the aquatic to the terrestrial habitat. In particular, the integument was subject to a number of …

Background With the increasing rate of antibiotic resistance in Acinetobacter, the World
Health Organization introduced the carbapenem-resistant isolates in the priority pathogens …

Skin secretions from frogs belonging to the genera Xenopus, Silurana, Hymenochirus, and
Pseudhymenochirus in the family Pipidae are a rich source of host-defense peptides with …

The rise in antibiotic-resistant strains of clinically important pathogens is a major threat to
global health. The World Health Organization (WHO) has recognized the urgent need to …

Antimicrobial peptides often show broad-spectrum activity due to a mechanism based on
bacterial membrane disruption, which also reduces development of permanent resistance, a …

The skin secretion of many amphibians contains an arsenal of bioactive molecules,
including hormone-like peptides (HLPs) acting as defense toxins against predators, and …

Poison frogs are well known for their ability to sequester alkaloids from their diet of leaf-litter
arthropods for use in defense against predators and pathogens. Australian frogs in the …

The skin of many amphibians produces a large repertoire of antimicrobial peptides that are
crucial in the first line of defense against microbial invasion. Despite the immense richness …

Skin secretions of frogs from the subfamily Xenopodinae (Xenopus+ Silurana) within the
family Pipidae are a rich source of antimicrobial peptides with therapeutic potential but …