Since their discovery in Drosophila, the heat shock proteins (Hsps) have been shown to
regulate both stress resistance and life-span. Aging is characterized by increased oxidative …

Rvb1 and Rvb2 are highly conserved and essential eukaryotic AAA+ proteins linked to a
wide range of cellular processes. AAA+ proteins are ATPases associated with diverse …

A common physiological response of organisms to environmental stresses is the increase in
expression of heat shock proteins (Hsps). In insects, this process has been widely examined …

A small number of heat-shock proteins have previously been shown to act protectively on
aggregation of several proteins containing an extended polyglutamine (polyQ) stretch, which …

We exposed adult male Drosophila melanogaster to cold, desiccation or starvation, and
examined expression of several genes during exposure and recovery. Frost was expressed …

Protein aggregation is a hallmark of many neuronal disorders, including the polyglutamine
disorder spinocerebellar ataxia 3 and peripheral neuropathies associated with the K141E …

The rapid cold-hardening (RCH) response increases the cold tolerance of insects by
protecting against non-freezing, cold-shock injury. Apoptosis, or programmed cell death …

The family of the mammalian small heat-shock proteins consists of 10 members
(sHSPs/HSPBs: HSPB1–HSPB10) that all share a highly conserved C-terminal alpha …

The authors are well suited to write such a book, having studied large natural populations at
the organismal and molecular levels of the heat shock response. Even during the heyday of …

Maternal investment is likely to have direct effects on offspring survival. In oviparous animals
whose embryos are exposed to the external environment, maternal provisioning of …