Environmental factors influencing the development and spread of antibiotic resistance

J Bengtsson-Palme, E Kristiansson… - FEMS microbiology …, 2018 - academic.oup.com
Antibiotic resistance and its wider implications present us with a growing healthcare crisis.
Recent research points to the environment as an important component for the transmission …

Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success

LS Redgrave, SB Sutton, MA Webber… - Trends in microbiology, 2014 - cell.com
Quinolone and fluoroquinolone antibiotics are potent, broad-spectrum agents commonly
used to treat a range of infections. Resistance to these agents is multifactorial and can be via …

Helicobacter pylori infection, its laboratory diagnosis, and antimicrobial resistance: a perspective of clinical relevance

S Ansari, Y Yamaoka - Clinical microbiology reviews, 2022 - Am Soc Microbiol
Despite the recent decrease in overall prevalence of Helicobacter pylori infection, morbidity
and mortality rates associated with gastric cancer remain high. The antimicrobial resistance …

Collateral sensitivity of antibiotic-resistant microbes

C Pál, B Papp, V Lázár - Trends in microbiology, 2015 - cell.com
Understanding how evolution of microbial resistance towards a given antibiotic influences
susceptibility to other drugs is a challenge of profound importance. By combining laboratory …

Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network

V Lázár, I Nagy, R Spohn, B Csörgő, Á Györkei… - Nature …, 2014 - nature.com
Understanding how evolution of antimicrobial resistance increases resistance to other drugs
is a challenge of profound importance. By combining experimental evolution and genome …

DNA supercoiling is a fundamental regulatory principle in the control of bacterial gene expression

CJ Dorman, MJ Dorman - Biophysical reviews, 2016 - Springer
Although it has become routine to consider DNA in terms of its role as a carrier of genetic
information, it is also an important contributor to the control of gene expression. This …

Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198

J Hawkey, S Le Hello, B Doublet… - Microbial …, 2019 - microbiologyresearch.org
Salmonella enterica serotype Kentucky can be a common causative agent of salmonellosis,
usually associated with consumption of contaminated poultry. Antimicrobial resistance …

Compensatory evolution of Pseudomonas aeruginosa's slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis

R La Rosa, E Rossi, AM Feist, HK Johansen… - Nature …, 2021 - nature.com
Long-term infection of the airways of cystic fibrosis patients with Pseudomonas aeruginosa
is often accompanied by a reduction in bacterial growth rate. This reduction has been …

Parallel evolutionary pathways to antibiotic resistance selected by biocide exposure

MA Webber, RN Whitehead, M Mount… - Journal of …, 2015 - academic.oup.com
Objectives Biocides are widely used to prevent infection. We aimed to determine whether
exposure of Salmonella to various biocides could act as a driver of antibiotic resistance …

Multidrug-resistant pathogens in the food supply

ME Doyle - Foodborne Pathogens and Disease, 2015 - liebertpub.com
Antimicrobial resistance, including multidrug resistance (MDR), is an increasing problem
globally. MDR bacteria are frequently detected in humans and animals from both more-and …