The placenta in preeclampsia

JM Roberts, C Escudero - Pregnancy Hypertension: An International …, 2012 - Elsevier
The root cause of preeclampsia is the placenta. Preeclampsia begins to abate with the
delivery of the placenta and can occur in the absence of a fetus but with the presence of …

[HTML][HTML] Update of syncytiotrophoblast derived extracellular vesicles in normal pregnancy and preeclampsia

D Tannetta, I Masliukaite, M Vatish, C Redman… - Journal of reproductive …, 2017 - Elsevier
The release of extracellular vesicles (EV) by the syncytiotrophoblast (STB) may be an
important mechanism by which the placenta signals to the mother. STB derived EV (STBEV) …

Preeclampsia 2012

E Eiland, C Nzerue, M Faulkner - Journal of pregnancy, 2012 - Wiley Online Library
Preeclampsia is a common complication of pregnancy associated with high maternal
morbidity and mortality and intrauterine fetal growth restriction. There is extensive evidence …

Tumor necrosis factor‐alpha, interleukin‐6, and interleukin‐10 levels are altered in preeclampsia: a systematic review and meta‐analysis

SY Lau, SJ Guild, CJ Barrett, Q Chen… - American journal of …, 2013 - Wiley Online Library
Problem Published reports testing the association between cytokine levels and
preeclampsia are conflicting. This comprehensive systematic review and meta‐analysis …

Human placental microRNAs and preeclampsia

D Chen, W Wang - Biology of reproduction, 2013 - academic.oup.com
MicroRNAs are a class of noncoding small RNAs that regulate the expression of nearly 30%
of all the human genes and participate in all fundamental cell processes. Genome-wide …

Preeclampsia and obesity—the preventive role of exercise

E Poniedziałek-Czajkowska, R Mierzyński… - International journal of …, 2023 - mdpi.com
Obesity is now recognized as a worldwide epidemic. An inadequate diet and reduced
physical activity are acknowledged as the leading causes of excess body weight. Despite …

Preeclampsia link to gestational hypoxia

W Tong, DA Giussani - Journal of developmental origins of health …, 2019 - cambridge.org
Complications of pregnancy remain key drivers of morbidity and mortality, affecting the
health of both the mother and her offspring in the short and long term. There is lack of …

Could vitamin D be effective in prevention of preeclampsia?

E Poniedziałek-Czajkowska, R Mierzyński - Nutrients, 2021 - mdpi.com
Prevention of preeclampsia (PE) remains one of the most significant problems in perinatal
medicine. Due to the possible unpredictable course of hypertension in pregnancy, primarily …

Key role of the endothelial TGF-β/ALK1/endoglin signaling pathway in humans and rodents pulmonary hypertension

B Gore, M Izikki, O Mercier, L Dewachter, E Fadel… - PloS one, 2014 - journals.plos.org
Mutations affecting transforming growth factor-beta (TGF-β) superfamily receptors, activin
receptor-like kinase (ALK)-1, and endoglin (ENG) occur in patients with pulmonary arterial …

where is the maternofetal interface?

LW Chamley, OJ Holland, Q Chen, CA Viall, PR Stone… - Placenta, 2014 - Elsevier
Ask where the maternofetal interface is and placental biologists will tell you, the
syncytiotrophoblast and extravillous cytotrophoblasts. While correct, this is not full extent of …