Chromosome alignment and biorientation is essential for mitotic progression and genomic
stability. Most chromosomes align at the spindle equator in a motor-independent manner …

Chromosome congression is essential for faithful chromosome segregation and genomic
stability in cell division. Centromere‐associated protein E (CENP‐E), a plus‐end‐directed …

CLASPs (cytoplasmic linker-associated proteins) are ubiquitous stabilizers of microtubule
dynamics, but their molecular targets at the microtubule plus-end are not understood. Using …

Kinesin motor proteins that drive intracellular transport share an overall architecture of two
motor domain-containing subunits that dimerize through a coiled-coil stalk. Dimerization …

Accurate chromosome segregation relies on microtubule end conversion, the ill-understood
ability of kinetochores to transit from lateral microtubule attachment to durable association …

In eukaryote cells, cargos are often transported cooperatively by kinesin motors and
nonmotor microtubule-associated proteins (MAPs). The prior in vitro experimental data …

Kinesins constitute a superfamily of microtubule (MT)-based motor proteins, which can
perform diverse biological functions in cells such as transporting vesicle, regulating MT …

Kinesin-14s constitute a subfamily of the large superfamily of adenosine triphosphate-
dependent microtubule-based motor proteins. Kinesin-14s have the motor domain at the C …

CENP-E is a large kinesin motor protein which plays pivotal roles in mitosis by facilitating
chromosome capture and alignment, and promoting microtubule flux in the spindle. So far, it …

In eukaryotes, meiosis is the genetic basis for sexual reproduction, which is important for
chromosome stability and species evolution. The defects in meiosis usually lead to …