COVID-19 mRNA vaccines: Platforms and current developments

GT Szabó, AJ Mahiny, I Vlatkovic - Molecular Therapy, 2022 - cell.com
Since the first successful application of messenger ribonucleic acid (mRNA) as a vaccine
agent in a preclinical study nearly 30 years ago, numerous advances have been made in …

Biomaterial-enabled therapeutic modulation of cGAS-STING signaling for enhancing antitumor immunity

Y Liu, Y Fei, X Wang, B Yang, M Li, Z Luo - Molecular Therapy, 2023 - cell.com
cGAS-STING signaling is a central component in the therapeutic action of most existing
cancer therapies. The accumulated knowledge of tumor immunoregulatory network in recent …

[HTML][HTML] Carrier-free mRNA vaccine induces robust immunity against SARS-CoV-2 in mice and non-human primates without systemic reactogenicity

S Abbasi, M Matsui-Masai, F Yasui, A Hayashi… - Molecular Therapy, 2024 - cell.com
Carrier-free naked mRNA vaccines may reduce the reactogenicity associated with delivery
carriers; however, their effectiveness against infectious diseases has been suboptimal. To …

SARS-CoV-2 variant Pathogenesis following primary infection and reinfection in Syrian hamsters

J Plunkard, K Mulka, R Zhou, P Tarwater, W Zhong… - Mbio, 2023 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
COVID-19, has evolved into multiple variants. Animal models are important to understand …

A qualitative comparison of the abbott SARS-CoV-2 IgG II quant assay against commonly used Canadian SARS-CoV-2 enzyme immunoassays in blood donor …

KT Abe, B Rathod, K Colwill, AC Gingras… - Microbiology …, 2022 - Am Soc Microbiol
Our group has previously used laboratory and commercially developed assays to
understand the IgG responses to SARS-CoV-2 antigens, including nucleocapsid (N), spike …