Biophysical characterisation of human LincRNA-p21 sense and antisense Alu inverted repeats
MH D'Souza, T Mrozowich, MD Badmalia… - Nucleic acids …, 2022 - academic.oup.com
Abstract Human Long Intergenic Noncoding RNA-p21 (LincRNA-p21) is a regulatory
noncoding RNA that plays an important role in promoting apoptosis. LincRNA-p21 is also …
noncoding RNA that plays an important role in promoting apoptosis. LincRNA-p21 is also …
Human DDX17 unwinds rift valley fever virus non-coding RNAs
Rift Valley fever virus (RVFV) is a mosquito-transmitted virus from the Bunyaviridae family
that causes high rates of mortality and morbidity in humans and ruminant animals. Previous …
that causes high rates of mortality and morbidity in humans and ruminant animals. Previous …
New perspective of small-molecule antiviral drugs development for RNA viruses
S Li, H Li, R Lian, J Xie, R Feng - Virology, 2024 - Elsevier
High variability and adaptability of RNA viruses allows them to spread between humans and
animals, causing large-scale infectious diseases which seriously threat human and animal …
animals, causing large-scale infectious diseases which seriously threat human and animal …
Molecular characterization of the RNA-protein complex directing− 2/− 1 programmed ribosomal frameshifting during arterivirus replicase expression
A Patel, EE Treffers, M Meier, TR Patel… - Journal of Biological …, 2020 - ASBMB
Programmed ribosomal frameshifting (PRF) is a mechanism used by arteriviruses like
porcine reproductive and respiratory syndrome virus (PRRSV) to generate multiple proteins …
porcine reproductive and respiratory syndrome virus (PRRSV) to generate multiple proteins …
Evaluating RNA structural flexibility: Viruses lead the way
CW Fairman, AML Lever, JC Kenyon - Viruses, 2021 - mdpi.com
Our understanding of RNA structure has lagged behind that of proteins and most other
biological polymers, largely because of its ability to adopt multiple, and often very different …
biological polymers, largely because of its ability to adopt multiple, and often very different …
Purification and characterization of inorganic pyrophosphatase for in vitro RNA transcription
Inorganic pyrophosphatase (iPPase) is an enzyme that cleaves pyrophosphate into two
phosphate molecules. This enzyme is an essential component of in vitro transcription (IVT) …
phosphate molecules. This enzyme is an essential component of in vitro transcription (IVT) …
An African tick flavivirus forming an independent clade exhibits unique exoribonuclease-resistant RNA structures in the genomic 3′-untranslated region
Tick-borne flaviviruses (TBFVs) infect mammalian hosts through tick bites and can cause
various serious illnesses, such as encephalitis and hemorrhagic fevers, both in humans and …
various serious illnesses, such as encephalitis and hemorrhagic fevers, both in humans and …
Analytical ultracentrifuge: an ideal tool for characterization of non-coding RNAs
Analytical ultracentrifugation (AUC) has emerged as a robust and reliable technique for
biomolecular characterization with extraordinary sensitivity. AUC is widely used to study …
biomolecular characterization with extraordinary sensitivity. AUC is widely used to study …
Investigating RNA–RNA interactions through computational and biophysical analysis
Numerous viruses utilize essential long-range RNA–RNA genome interactions, specifically
flaviviruses. Using Japanese encephalitis virus (JEV) as a model system, we …
flaviviruses. Using Japanese encephalitis virus (JEV) as a model system, we …
Biochemically investigating the roles of papain-like proteases from+ ssRNA viruses in replication and innate immune suppression
A Patel - 2021 - mspace.lib.umanitoba.ca
Positive-sense single-stranded RNA (+ ssRNA) viruses are diverse in the way their
genomes are packaged, polyproteins are arranged, and the hosts they infect. They often …
genomes are packaged, polyproteins are arranged, and the hosts they infect. They often …