Physician Global Assessment (PGA) and Psoriasis Area and Severity Index (PASI): why do both? A systematic analysis of randomized controlled trials of biologic …

A Robinson, M Kardos, AB Kimball - Journal of the American Academy of …, 2012 - Elsevier
BACKGROUND: Although there are many psoriasis assessment tools currently published,
one of the unmet needs in psoriasis research remains consensus about the single best …

Off-label biologic regimens in psoriasis: a systematic review of efficacy and safety of dose escalation, reduction, and interrupted biologic therapy

EA Brezinski, AW Armstrong - PLoS One, 2012 - journals.plos.org
Objectives While off-label dosing of biologic treatments may be necessary in selected
psoriasis patients, no systematic review exists to date that synthesizes the efficacy and …

European S3-guidelines on the systemic treatment of psoriasis vulgaris

D Pathirana, AD Ormerod, P Saiag, C Smith… - Journal of the …, 2009 - art.torvergata.it
European S3-Guidelines on the systemic treatment of psoriasis vulgaris D Pathirana, AD
Ormerod, P Saiag, C Smith, PI Spuls, A Na Page 1 JEADV october 2009, volume 23 …

The effect of weight on the efficacy of biologic therapy in patients with psoriasis

L Clark, M Lebwohl - Journal of the American Academy of Dermatology, 2008 - Elsevier
BACKGROUND: The prevalence of obesity is rapidly increasing in the United States.
Patients with psoriasis, in particular, tend to be above normal weight. Three of the 5 …

Alefacept in combination with methotrexate for the treatment of psoriatic arthritis: results of a randomized, double‐blind, placebo‐controlled study

PJ Mease, DD Gladman… - Arthritis & Rheumatism …, 2006 - Wiley Online Library
Objective To evaluate the efficacy and safety of alefacept in combination with methotrexate
(MTX) for the treatment of psoriatic arthritis (PsA). Methods Patients were eligible for this …

Recent trends in systemic psoriasis treatment costs

V Beyer, SE Wolverton - Archives of dermatology, 2010 - jamanetwork.com
Objectives To analyze the current total cost of systemic therapy for psoriasis and to compare
annual trends in the cost of both generic and brand-name therapies with trends in the …

[HTML][HTML] Which antipsoriatic drug has the fastest onset of action?—Systematic review on the rapidity of the onset of action

A Nast, B Sporbeck, S Rosumeck, D Pathirana… - Journal of Investigative …, 2013 - Elsevier
The time necessary for a treatment to become effective is crucial for patients and physicians
but has been largely neglected in the reporting and comparison of clinical trials in …

[HTML][HTML] Update on the natural history and systemic treatment of psoriasis

SK Richardson, JM Gelfand - Advances in dermatology, 2008 - ncbi.nlm.nih.gov
Psoriasis is a common inflammatory disease of the skin and joints. Its etiology remains
unknown, however, it has been linked to complex interactions between predisposing genes …

Advances in the treatment of moderate-to-severe plaque psoriasis

RN Herrier - American Journal of Health-System Pharmacy, 2011 - academic.oup.com
Purpose Advances in the treatment of moderate-to-severe plaque psoriasis, including new
biological agents and related drugs, are reviewed. Summary Most patients with psoriasis …

Representation of older adults in randomized controlled trials on systemic treatment in plaque psoriasis: a systematic review

MJ Schaap, MEC van Winden, MMB Seyger… - Journal of the American …, 2020 - Elsevier
Background Psoriasis is frequently seen in older patients, and systemic treatment is often
indicated. Randomized controlled trials (RCTs) generally maintain strict inclusion and …