In vivo brain MR spectroscopy in gliomas: clinical and pre-clinical chances

F Padelli, F Mazzi, A Erbetta, L Chiapparini… - Clinical and …, 2022 - Springer
Purpose Gliomas, the most common primary brain tumours, have recently been re-classified
incorporating molecular aspects with important clinical, prognostic, and predictive …

[图书][B] Dimethyl sulfoxide (DMSO) in trauma and disease

SW Jacob, JC de la Torre - 2015 - books.google.com
For the first time, the collective data on the biological, chemical, and medical actions of
DMSO are presented and analyzed from the published scientific literature. This book …

DCE@ urLAB: a dynamic contrast-enhanced MRI pharmacokinetic analysis tool for preclinical data

JE Ortuño, MJ Ledesma-Carbayo, RV Simões… - BMC …, 2013 - Springer
Background DCE@ urLAB is a software application for analysis of dynamic contrast-
enhanced magnetic resonance imaging data (DCE-MRI). The tool incorporates a friendly …

MRSI‐based molecular imaging of therapy response to temozolomide in preclinical glioblastoma using source analysis

T Delgado‐Goñi, S Ortega‐Martorell… - NMR in …, 2016 - Wiley Online Library
Characterization of glioblastoma (GB) response to treatment is a key factor for improving
patients' survival and prognosis. MRI and magnetic resonance spectroscopic imaging …

Molecular imaging coupled to pattern recognition distinguishes response to temozolomide in preclinical glioblastoma

T Delgado‐Goñi, M Julià‐Sapé… - NMR in …, 2014 - Wiley Online Library
Non‐invasive monitoring of response to treatment of glioblastoma (GB) is nowadays carried
out using MRI. MRS and MR spectroscopic imaging (MRSI) constitute promising tools for this …

Stimulation‐induced transient changes in neuronal activity, blood flow and N‐acetylaspartate content in rat prefrontal cortex: A chemogenetic fMRS‐BOLD study

MH Baslow, CK Cain, R Sears, DA Wilson… - NMR in …, 2016 - Wiley Online Library
Brain activation studies in humans have shown the dynamic nature of neuronal N‐
acetylaspartate (NAA) and N‐acetylaspartylglutamate (NAAG) based on changes in their …

Development of a transplantable glioma tumour model from genetically engineered mice: MRI/MRS/MRSI characterisation

M Ciezka, M Acosta, C Herranz, JM Canals… - Journal of neuro …, 2016 - Springer
The initial aim of this study was to generate a transplantable glial tumour model of low-
intermediate grade by disaggregation of a spontaneous tumour mass from genetically …

Toxicity studies on intrathecal injection of low dose of DMSO used for cryopreservation of human astrocytes in mice

T Sonnenfeld, E Rauchbach, R Downey… - 2023 - researchsquare.com
Background AstroRx® is an allogeneic cell therapy, composed of healthy and functional
human astrocytes derived from pluripotent embryonic stem cells. An intrathecal injection of a …

Applications of spin–spin couplings

K Kamieńska-Trela, J Wójcik - 2014 - books.rsc.org
In this chapter, which is devoted to applications of spin–spin couplings, the literature
published between June 2012 and May 2013 has been reviewed. The data included has …

On the road to improve glioblastoma therapy follow-up. Immune microenvironment: what is behind the MRSI-based nosological images?

M Calero Pérez - 2022 - ddd.uab.cat
Glioblastoma (GB) is an aggressive brain tumour with poor survival. Improvements in both
therapeutic and follow-up strategies are urgently needed. In this work, we described an …