Interferon-induced transmembrane proteins (IFITMs) are broad spectrum antiviral factors that
inhibit the entry of a wide range of clinically important pathogens including influenza A virus …

Interferons (IFNs) are important cytokines that regulate immune responses through the
activation of hundreds of genes, including interferon-induced transmembrane proteins …

Cholesterol and its oxidized forms, oxysterols, are ingested from foods and are synthesized
de novo. Cholesterol and oxysterols influence molecular and cellular events and …

ABSTRACT COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) has had a devastating impact on global public health, emphasizing the …

Cholesterol, as an important component in mammalian cells, is efficient for viral entry,
replication, and assembly. Oxysterols especially hydroxylated cholesterols are recognized …

Abstract Background The Coronavirus disease 2019 (COVID-19) pandemic occurred due to
the dispersion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Severe …

Human interferon-induced transmembrane (IFITM) proteins inhibit the fusion of a broad
spectrum of enveloped viruses, both when expressed in target cells and when present in …

The dispanins are a family of 15 transmembrane proteins that have diverse and often
unclear physiological functions. Many dispanins, including synapse differentiation induced …

Uncontrolled chronic inflammation, in most cases due to excessive cytokine signaling
through their receptors, is known to contribute to the development of tumorigenesis …

Interferons (IFNs) are antiviral cytokines that defend against viral infections by inducing the
expression of interferon-stimulated genes (ISGs). Interferon-inducible transmembrane …