Design and application of antimicrobial peptide conjugates
A Reinhardt, I Neundorf - International journal of molecular sciences, 2016 - mdpi.com
Antimicrobial peptides (AMPs) are an interesting class of antibiotics characterized by their
unique antibiotic activity and lower propensity for developing resistance compared to …
unique antibiotic activity and lower propensity for developing resistance compared to …
The future of aminoglycosides: the end or renaissance?
Although aminoglycosides have been used as antibacterials for decades, their use has
been hindered by their inherent toxicity and the resistance that has emerged to these …
been hindered by their inherent toxicity and the resistance that has emerged to these …
PVP-coated silver nanoparticles block the transmission of cell-free and cell-associated HIV-1 in human cervical culture
Background Previous in vitro studies have demonstrated that polyvinylpyrrolidone coated
silver nanoparticles (PVP-coated AgNPs) have antiviral activity against HIV-1 at non …
silver nanoparticles (PVP-coated AgNPs) have antiviral activity against HIV-1 at non …
Comprehensive review of chemical strategies for the preparation of new aminoglycosides and their biological activities
NT Chandrika, S Garneau-Tsodikova - Chemical Society Reviews, 2018 - pubs.rsc.org
A systematic analysis of all synthetic and chemoenzymatic methodologies for the
preparation of aminoglycosides for a variety of applications (therapeutic and agricultural) …
preparation of aminoglycosides for a variety of applications (therapeutic and agricultural) …
Potential for the development of a new generation of aminoglycoside antibiotics
AN Tevyashova, KS Shapovalova - Pharmaceutical Chemistry Journal, 2021 - Springer
The present review summarizes recent publications devoted to aminoglycosides that study
the main types of resistance to antibiotics of this class and the main directions of chemical …
the main types of resistance to antibiotics of this class and the main directions of chemical …
Aminoglycoside conjugation for RNA targeting: antimicrobials and beyond
K Aradi, A Di Giorgio, M Duca - Chemistry–A European Journal, 2020 - Wiley Online Library
Natural aminoglycosides are therapeutically useful antibiotics and very efficient RNA
ligands. They are oligosaccharides that contain several ammonium groups able to interfere …
ligands. They are oligosaccharides that contain several ammonium groups able to interfere …
Synthesis and antibacterial activity of amphiphilic lysine-ligated neomycin B conjugates
S Bera, GG Zhanel, F Schweizer - Carbohydrate research, 2011 - Elsevier
Amphiphilic lysine-ligated neomycin B building blocks were prepared by reductive
amination of a protected C5 ″-modified neomycin B-based aldehyde and side chain …
amination of a protected C5 ″-modified neomycin B-based aldehyde and side chain …
Structural-Based Virtual Screening of FDA-Approved Drugs Repository for NSP16 Inhibitors, Essential for SARS-COV-2 Invasion Into Host Cells: Elucidation From MM …
NSP16 is one of the structural proteins of the severe acute respiratory syndrome coronavirus-
2 (SARS-CoV-2) necessary for its entrance to the host cells. It exhibits 2'O-methyl …
2 (SARS-CoV-2) necessary for its entrance to the host cells. It exhibits 2'O-methyl …
Recent advances in understanding the molecular mechanisms of HIV-1 entry and fusion: revisiting current targets and considering new options for therapeutic …
I Markovic, KA Clouse - Current HIV Research, 2004 - ingentaconnect.com
Recent advances in our understanding of the cellular and molecular mechanisms of HIV-1
entry provide the basis for novel therapeutic strategies that prevent viral penetration of the …
entry provide the basis for novel therapeutic strategies that prevent viral penetration of the …
Docking and 3D-QSAR studies of BMS-806 analogs as HIV-1 gp120 entry inhibitors
BMS-378806 (BMS-806) is a small molecule that blocks the binding of host-cell CD4 with
viral gp120 protein and therefore inhibits the first steps of HIV-1 infection. Recently, 36 …
viral gp120 protein and therefore inhibits the first steps of HIV-1 infection. Recently, 36 …