Antimicrobial peptides (AMPs) are an interesting class of antibiotics characterized by their
unique antibiotic activity and lower propensity for developing resistance compared to …

Although aminoglycosides have been used as antibacterials for decades, their use has
been hindered by their inherent toxicity and the resistance that has emerged to these …

Background Previous in vitro studies have demonstrated that polyvinylpyrrolidone coated
silver nanoparticles (PVP-coated AgNPs) have antiviral activity against HIV-1 at non …

A systematic analysis of all synthetic and chemoenzymatic methodologies for the
preparation of aminoglycosides for a variety of applications (therapeutic and agricultural) …

The present review summarizes recent publications devoted to aminoglycosides that study
the main types of resistance to antibiotics of this class and the main directions of chemical …

Natural aminoglycosides are therapeutically useful antibiotics and very efficient RNA
ligands. They are oligosaccharides that contain several ammonium groups able to interfere …

Amphiphilic lysine-ligated neomycin B building blocks were prepared by reductive
amination of a protected C5 ″-modified neomycin B-based aldehyde and side chain …

NSP16 is one of the structural proteins of the severe acute respiratory syndrome coronavirus-
2 (SARS-CoV-2) necessary for its entrance to the host cells. It exhibits 2'O-methyl …

Recent advances in our understanding of the cellular and molecular mechanisms of HIV-1
entry provide the basis for novel therapeutic strategies that prevent viral penetration of the …

BMS-378806 (BMS-806) is a small molecule that blocks the binding of host-cell CD4 with
viral gp120 protein and therefore inhibits the first steps of HIV-1 infection. Recently, 36 …