Etiology and pathogenesis of preeclampsia: current concepts

GA Dekker, BM Sibai - American journal of obstetrics and gynecology, 1998 - Elsevier
The etiology of preeclampsia is unknown. At present, 4 hypotheses are the subject of
extensive investigation, as follows:(1) Placental ischemia—Increased trophoblast …

Prospects for the use of antioxidant therapies

SRJ Maxwell - Drugs, 1995 - Springer
Free radical oxidative stress has been implicated in the pathogenesis of a variety of human
diseases. Natural antioxidant defences have been found to be defective in many of the same …

Oxidative stress in the pathogenesis of preeclampsia

CA Hubel - Proceedings of the Society for Experimental …, 1999 - Wiley Online Library
The etiology and pathogenesis of the pregnancy syndrome preeclampsia remain poorly
understood. There is substantial evidence to suggest that the diverse manifestations of …

[HTML][HTML] Comprehensive analysis of oxidative stress markers and antioxidants status in preeclampsia

A Taravati, F Tohidi - Taiwanese Journal of Obstetrics and Gynecology, 2018 - Elsevier
Preeclampsia is a hypertensive disorder in pregnant women, which can be the leading
cause of maternal and neonatal death or premature birth. Although the cause of …

Oxidative stress and preeclampsia: rationale for antioxidant clinical trials

MTM Raijmakers, R Dechend, L Poston - Hypertension, 2004 - Am Heart Assoc
Preeclampsia remains a frequent and potentially dangerous complication of pregnancy. The
cause remains largely unknown, but oxidative stress and a generalized inflammatory state …

Role of oxidative stress in intrauterine growth restriction

A Biri, N Bozkurt, A Turp, M Kavutcu… - Gynecologic and …, 2007 - karger.com
Aims: The objectives of this study were to determine the role of oxidative stress in
intrauterine growth restriction (IUGR) and to investigate the possible molecular mechanism …

Double blind, cluster randomised trial of low dose supplementation with vitamin A or βcarotene on mortality related to pregnancy in Nepal

KP West Jr, J Katz, SK Khatry, SC LeClerq, EK Pradhan… - Bmj, 1999 - bmj.com
Objective: To assess the impact on mortality related to pregnancy of supplementing women
of reproductive age each week with a recommended dietary allowance of vitamin A, either …

Causes of oxidative stress in the pre-and perinatal period

E Gitto, RJ Reiter, M Karbownik, D Tan, P Gitto… - Neonatology, 2002 - karger.com
Oxidative stress may be defined as an imbalance between pro-oxidant and antioxidant
forces resulting in an overall pro-oxidant insult. Pregnancy is a physiological state …

[PDF][PDF] Epidemiology of pregnancy-induced hypertension

J Zhang, J Zeisler, MC Hatch, G Berkowitz - Epidemiologic reviews, 1997 - Citeseer
Pregnancy-induced hypertension (PIH) is a syndrome of hypertension with or without
proteinuria and edema, with the clinical manifestation usually occurring late in pregnancy …

Invasive cytotrophoblasts manifest evidence of oxidative stress in preeclampsia

A Many, CA Hubel, SJ Fisher, JM Roberts… - The American journal of …, 2000 - Elsevier
In preeclampsia, poor placental perfusion may result in maternal endothelial dysfunction, but
the pathways involved are largely unknown. Candidate placental mediators include …