Glaucoma: now and beyond

H Jayaram, M Kolko, DS Friedman, G Gazzard - The Lancet, 2023 - thelancet.com
The glaucomas are a group of conditions leading to irreversible sight loss and characterised
by progressive loss of retinal ganglion cells. Although not always elevated, intraocular …

Recent advances of smart materials for ocular drug delivery

X Wang, F Luan, H Yue, C Song, S Wang… - Advanced drug delivery …, 2023 - Elsevier
Owing to the variety and complexity of ocular diseases and the natural ocular barriers, drug
therapy for ocular diseases has significant limitations, such as poor drug targeting to the site …

[HTML][HTML] Topical medication therapy for glaucoma and ocular hypertension

T Wang, L Cao, Q Jiang, T Zhang - Frontiers in Pharmacology, 2021 - frontiersin.org
Glaucoma is one of the most common causes of blindness, thus seriously affecting people's
health and quality of life. The topical medical therapy is as the first line treatment in the …

Primary glaucomas in adults: Epidemiology and public health‐A review

TF Reis, JS Paula, JM Furtado - Clinical & experimental …, 2022 - Wiley Online Library
Glaucoma is a mixed group of optic neuropathies that lead to irreversible visual field loss
and blindness if left untreated. It is estimated that 3.5% of the global population aged 40 to …

Association of health literacy and health care utilization among glaucoma patients

BT Cheng, AP Tanna - Journal of Glaucoma, 2023 - journals.lww.com
Purpose: Previous studies found LHL is associated with increased difficulty with treatment
adherence among adults with glaucoma, which can lead to poor outcomes. This study …

Polygenic Risk Scores Driving Clinical Change in Glaucoma

A Kolovos, MM Hassall, OM Siggs… - Annual Review of …, 2024 - annualreviews.org
Glaucoma is a clinically heterogeneous disease and the world's leading cause of
irreversible blindness. Therapeutic intervention can prevent blindness but relies on early …

[HTML][HTML] Vitamin intake and glaucoma risk: A systematic review and meta-analysis

FF Han, XX Fu - Journal Français d'Ophtalmologie, 2022 - Elsevier
There is currently a lack of high-quality research on the best dietary recommendations for
patients with early glaucoma or at high risk for glaucoma. This meta-analysis aims to clarify …

Polygenic Risk Scores for Glaucoma Onset in the Ocular Hypertension Treatment Study

RK Singh, Y Zhao, T Elze, J Fingert… - JAMA …, 2024 - jamanetwork.com
Importance Primary open-angle glaucoma (POAG) is a highly heritable disease, with 127
identified risk loci to date. Polygenic risk score (PRS) may provide a clinically useful …

[HTML][HTML] Long-term impact of immediate versus delayed treatment of early glaucoma: results from the Early Manifest Glaucoma Trial

A Heijl, D Peters, B Bengtsson - American Journal of Ophthalmology, 2023 - Elsevier
PURPOSE To compare long-term visual outcomes in the 2 arms of the Early Manifest
Glaucoma Trial (EMGT) and determine if delayed treatment was associated with a penalty in …

Six-Year Incidence and Risk Factors for Primary Open-Angle Glaucoma and Ocular Hypertension: The Singapore Epidemiology of Eye Diseases Study

S Thakur, R Lavanya, M Yu, YC Tham, Z Da Soh… - Ophthalmology …, 2024 - Elsevier
Objective To determine the incidence and risk factors for primary open-angle glaucoma
(POAG) and ocular hypertension (OHT) in a multiethnic Asian population. Design Population …